“PO-80 | Real-world effectiveness of atogepant for the preventive treatment of migraine in a cohort of multi -refractory patients: a single center study: M. De Luca,1 L. Ferraù,1 A. Cafarchio,2 M.S. Adragna,1 M. Autunno1 | 1Unit of Neurology and Neuromuscular Diseases, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy; 2Department of Medicine and Health Sciences ‘Vincenzo Tibero’ DIMES, University of Molise, Campobasso, Italy” (2025) Confinia Cephalalgica, 35(S1). doi:10.4081/cc.2025.15904.