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• P050 | MIGRAINE PRODROMAL SYMPTOMS AND THEIR CLINICAL MANIFESTATIONS, AN OBSERVATIONAL MULTICENTER STUDY

  G. Dalla Volta¹, M. Cortinovis¹, P. Merlo², A. Viganò³, V. Rebecchi⁴, S. Mazza⁴, M. Gennuso⁵, N. Ghiotto⁶, E. Guaschino⁶, G. Sances⁶, M. Bolchini¹ | ¹Neurology Unit and Headache Center, Istituto Clinico Città Di Brescia, Italy; ²Neurology Unit, Humanitas Gavazzeni and University HUNIMED, Bergamo, Italy; ³Neurology Unit, Humanitas Gavazzeni, Bergamo, Italy; ⁴Neurology Unit, Ospedale Civile di Voghera – ASST Pavia, Italy; ⁵Casa di Cura Ancelle della Carità, Fondazione Camplani, Cremona, Italy; ⁶Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.16006

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• P079 | THE ROLE OF GUT MICROBIOTA IN MIGRAINE SUBJECTS TREATED WITH ANTI-CGRP MONOCLONAL ANTIBODIES: RESULTS THE SPHERA PROJECT

  F. Muscariello^1|2, G. Vaghi^1|2, R. Greco², V. Grillo^1|2, M. Corrado², F. Cammarota^1|2, B. Agostini^1|2, M. Giraudo^1|2, C. Angeli^1|2, M. Allena², E. Guaschino², N. Ghiotto², R. Ornello³, S. Sacco³, C. Demartini², M. Francavilla^1|2, S. Facchetti^1|2, V. Pazienza⁴, D. Sproviero², G. Sances², C. Tassorelli^1|2, R. De Icco^1|2 | ¹Department of Brain and Behavioral Sciences, University of Pavia, Italy; ²Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy; ³Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; ⁴Division of Gastroenterology, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.16035

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• OC01 | DECODING THE BIOCHEMICAL SIGNATURE OF TREATMENT-RESISTANT MIGRAINE: SEARCHING FOR DISEASE PHENOTYPES AND NOVEL THERAPEUTIC TARGETS

  B. Agostini^1|2, R. Greco², G. Vaghi^1|2, V. Grillo^1|2, M. Corrado², F. Cammarota^1|2, C. Angeli^1|2, F. Muscariello^1|2, M. Giraudo^1|2, M. Allena², E. Guaschino², N. Ghiotto², C. Demartini², M. Francavilla^1|2, S. Facchetti^1|2, V. Franco^2|3, G. Sances², C. Tassorelli^1|2, R. De Icco^1|2 | ¹Department of Brain and Behavioral Sciences, University of Pavia, Italy; ²Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy; ³Department of Internal Medicine and Therapeutics, University of Pavia, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15939

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• P077 | UNRAVELING THE COMPLEXITY OF MEDICATION-OVERUSE HEADACHE: CLINICAL AND BEHAVIORAL PREDICTORS OF 12-MONTH OUTCOMES

  N. Ghiotto¹, E. Guaschino¹, S. Pazzi¹, L. Toppi², D. Mazzotta², T. Filidei², M. Allena¹, R. De Icco^1|2, D. Martinelli¹, G. Vaghi^1|2, G. Sances¹, C. Tassorelli^1|2 | ¹Headache Science and Neurorehabilitation Unit, IRCCS C. Mondino Foundation, Pavia, Italy; ²Department of Brain and Behavioral Sciences, University of Pavia, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.16033

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• OC06 | UNRAVELING THE SPECTRUM OF MIGRAINE RESISTANT TO TREATMENT: THE ROLE OF MRI RESTING-STATE FUNCTIONAL CONNECTIVITY IN MIGRAINE SUBJECTS TREATED WITH ANTI-CGRP MONOCLONAL ANTIBODIES

  M. Giraudo^1|2, D. Martinelli², G. Vaghi^1|2, G. Castellazzi², M. Corrado², F. Cammarota^1|2, B. Agostini^1|2, F. Muscariello^1|2, C. Angeli^1|2, V. Grillo^1|2, R. Greco², C. Demartini^1|2, M. Francavilla^1|2, S. Facchetti^1|2, A. Pichiecchio^1|3, M. Allena², E. Guaschino², N. Ghiotto², G. Sances², C. Tassorelli^1|2, R. De Icco^1|2 | ¹Department of Brain and Behavioral Sciences, University of Pavia, Italy; ²Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy; ³Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15944

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