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• P034 | BODY WEIGHT CHANGES DURING ATOGEPANT THERAPY: A CASE REPORT AND NARRATIVE REVIEW OF THE METABOLIC ROLE OF CGRP

  C. Rita Tamborino, G. Difonzo, F. Domenico Pellicano, A. Fallacara, D. Paolicelli, M. Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15990

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• OC18 | LONG-TERM EFFECTIVENESS, SAFETY AND TOLERABILITY OF ATOGEPANT IN THE PREVENTION OF MIGRAINE: A MULTICENTRIC, PROSPECTIVE OBSERVATIONAL, REAL WORLD STUDY (THE 48-WEEK STAR STUDY)

  F. Vernieri^1|2, L. Francesco Iannone³, M. Marcosano^1|2, L. Fofi¹, F. Lo Castro⁴, G. Sebastianelli⁵, F. De Santis⁶, M. Corrado⁷, R. Ornello⁶, L. Grazzi⁸, D. Antonio Montisano⁸, F. De Cesaris⁹, A. Munafò⁹, G. Avino¹⁰, M. Trimboli¹¹, M. Albanese¹², A. Russo¹³, M. Silvestro¹³, G. Dalla Volta¹⁴, M. Romozzi¹⁵, P. Calabresi¹⁵, A. Boccalini⁴, P. Merlo¹⁶, M. Pia Prudenzano¹⁷, M. Rosaria Valente¹⁸, I. Rainero¹⁹, G. Giuliani²⁰, M. Altieri²⁰, A. Doretti²¹, G. Vaghi^7|22, F. Pistoia⁶, D. Ferrandi²³, S. Battistini²⁴, G. Coppola⁵, S. Guerzoni⁴, S. Sacco^6|25, C. Tassorelli^7|22, C. Altamura^1|2 | ¹Headache and Neurosonology Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy; ²Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Italy; ³Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy; ⁴Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico Di Modena, Italy; ⁵Sapienza University of Rome, Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino, Latina, Italy; ⁶Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy; ⁷Headache Science and Neurorehabilitation Centre, IRCCS Mondino Foundation, Pavia, Italy; ⁸Headache Center IRCCS Fondazione Istituto Neurologico "Carlo Besta", Italy; ⁹Headache center and clinical pharmacology, AOU Careggi, Firenze, Italy; ¹⁰Neurology Unit, Ospedale Santo Stefano, USL Toscana Centro, Prato, Italy; ¹¹Azienda Ospedaliera-universitaria "Renato Dulbecco", Catanzaro, Italy; ¹²Department of Systems Medicine, University of Rome Tor Vergata, Italy; ¹³Headache Center, Department of Medical, Surgical, Neurological, Metabolic and Aging Sciences, Second University of Naples, Italy; ¹⁴U.O Neurologia, Istituto Clinico Città di Brescia, Gruppo San Donato, Italy; ¹⁵Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ¹⁶UO di Neurologia, Humanitas Gavazzeni, Bergamo, Italy; ¹⁷Clinica Neurologica "L. Amaducci", Azienda Ospedaliero-Universitaria Consorziale Policlinico di Bari, Italy; ¹⁸Clinica Neurologica ASUFC, Dipartimento di Medicina DMED Università di Udine, Italy; ¹⁹Headache Center, Department of Neuroscience, University of Torino, Italy; ²⁰Department of Human Neuroscience, Sapienza University of Rome, Italy; ²¹IRCCS Istituto Auxologico Italiano, Milano, Italy; ²²Department of Brain and Behavioural Sciences, University of Pavia, Italy; ²³SC Neurologia, Azienda Ospedaliero Universitaria Santi Antonio e Biagio, Alessandria, Italy; ²⁴Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy; ²⁵Neurology and Stroke Unit, ASL 1 Abruzzo, Avezzano-Sulmona-L’Aquila, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15956

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• P023 | SUSTAINED CLINICAL RESPONSE TO ATOGEPANT AFTER FAILURE OF FOUR ANTI-CGRP MONOCLONAL ANTIBODIES IN HIGHLY RESISTANT CHRONIC MIGRAINE

  G. Difonzo, C. Rita Tamborino, F. Domenico Pellicano, A. Fallacara, D. Paolicelli, M. Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15979

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• P093 | GAINER-AI: PREDICTING ACUTE RIMEGEPANT RESPONSE IN MIGRAINE USING MACHINE LEARNING IN A MULTICENTER REAL-WORLD COHORT

  M. Romozzi^1|2, A. Lokhawandala³, G. Vaghi^4|5, G. Sebastianelli⁶, R. Ornello⁷, F. Casillo⁶, A. Russo⁸, M. Silvestro⁸, F. Pistoia⁹, G. Saporito⁹, G. Dalla Volta¹⁰, M. Bolchini¹⁰, A. Burgalassi¹¹, G. Vigani¹¹, D. Antonio Montisano¹², L. Grazzi¹², M. Pia Prudenzano¹³, D. Mascarella¹⁴, E. Mampreso¹⁵, G. Avino¹⁶, M. Valente¹⁷, G. Carlucci¹⁸, S. Guerzoni¹⁹, S. Battistini²⁰, A. Granato²¹, E. Maria Piella²², I. Rainero²², M. Albanese²³, M. Trimboli²⁴, A. Doretti²⁵, F. De Santis⁷, S. Sacco⁷, C. Tassorelli^4|5, S. Di Tella²⁶, C. Vollono^1|2, P. Calabresi^1|2, R. De Icco^4|5, L. Francesco Iannone²⁷ | ¹Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Rome, Italy; ²Neurologia, Dipartimento di neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; ³Drexel University, Philadelphia, USA; ⁴Department of Brain and Behavioral Sciences, University of Pavia, Italy; ⁵Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy; ⁶Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina, Italy; ⁷Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy; ⁸Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy; ⁹Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; ¹⁰Headache Center of Clinical Neurology of Istituto Clinico Città Di Brescia, Italy; ¹¹Department of Health Sciences, University of Florence, Italy; ¹²Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; ¹³Headache Center, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari, Italy; ¹⁴IRCCS Istituto Di Scienze Neurologiche Di Bologna, Programma Cefalee e Algie Facciali, Italy; ¹⁵Headache Centre, Neurology - Euganea, Health Unit, Padua, Italy; ¹⁶Neurology Unit, Ospedale Santo Stefano, USL Toscana Centro, Prato, Italy; ¹⁷Clinical Neurology, Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero Santa Maria Della Misericordia, Udine, Italy; ¹⁸NEUROFARBA Department, University of Florence - AOU Careggi, Italy; ¹⁹Digital and Predictive Medicine, Pharmacology, Clinical Metabolic Toxicology-Headache Center and Drug Abuse, Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico, Modena, Italy; ²⁰Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy; ²¹Headache Centre, Clinical Unit of Neurology, School of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, ASUGI, University of Trieste, Italy; ²²Department of Neurosciences “Rita Levi Montalcini”, University of Turin, Italy; ²³Unit of Neurology, Department of Systems Medicine, Tor Vergata University, Rome, Italy; Unit of Neurology - IRCCS Neuromed, Pozzilli (IS), Italy; ²⁴Headache Centre, Neurology Unit, AOU Renato Dulbecco, Catanzaro, Italy; ²⁵Department of Neurology- Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy; ²⁶Dipartimento di Psicologia, Università Cattolica del Sacro Cuore, Milan, Italy; ²⁷Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.16049

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