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• P032 | IMPROVEMENT IN DEPRESSIVE AND ANXIETY SYMPTOMS DURING EPTINEZUMAB TREATMENT: A POST-HOC ANALYSIS FROM THE TACHIS STUDY

  E.M. Piella¹, A.M. Chiarandon¹, V. Batti¹, D.A. Montisano², L. F. Iannone³, C. Fasano⁴, G. Sebastianelli⁵, G. Coppola⁵, D. Ferrandi⁶, C. Lanni⁷, M.P. Prudenzano⁸, M. De Tommaso⁹, P. Merlo¹⁰, A. Viganò¹⁰, F. De Cesaris¹¹, A. Chiarugi¹¹, A. Munafò¹¹, F. Pistoia¹², R. Ornello¹², S. Sacco¹², A. Doretti¹³, L. Grazzi², F. Lo Castro¹⁴, R. Allamprese¹⁴, R. De Icco^15|16, G. Vaghi^15|16, C. Tassorelli^15|16, G. Avino¹⁷, M. Romozzi¹⁸, C. Vollono¹⁸, P. Calabresi¹⁸, S. Battistini¹⁹, A. Rufa¹⁹, M. Albanese²⁰, M. Trimboli²¹, G. Carlucci⁴, M. Silvestro²², A. Russo²², M. Valente²³, L. Fofi²⁴, M. Marcosano²⁴, P. Geppetti²⁵, C. Altamura²⁴, F. Vernieri²⁴, E. Rubino¹, I. Rainero¹, S. Guerzoni¹⁴ | ¹Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Italy; ²Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy; ³Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy; ⁴NEUROFARBA Department, University of Florence - Neurologia, AOU Careggi, Italy; ⁵Sapienza University of Rome, Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino, Latina, Italy; ⁶AOU Alessandria, SC Neurologia, Italy; ⁷Psicologia AOU Alessandria, Italy; ⁸Clinica Neurologica "L. Amaducci", Azienda Ospedaliero-Universitaria Consorziale di Bari, Italy; ⁹Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Italy; ¹⁰UO di Neurologia, Humanitas Gavazzeni, Bergamo, Italy; ¹¹Headache center and Clinical pharmacology unit, AOU Careggi, Florence, Italy; ¹²Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; ¹³Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milano, Italy; ¹⁴Digital and Predictive Medicine, Pharmacology, Clinical Metabolic Toxicology-Headache Center and Drug Abuse, Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico, Modena, Italy; ¹⁵Department of Brain and Behavioral Sciences, University of Pavia, Italy; ¹⁶Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy; ¹⁷SOC Neurologia, Ospedale di Prato, Italy; ¹⁸Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; ¹⁹Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy; ²⁰Unit of Neurology, Department of Systems Medicine, University of Rome Tor Vergata, Italy; ²¹Headache Center, Unit of Neurology, AOU Renato Dulbecco, Catanzaro, Italy; ²²Inter-departmental Program of Headache Medicine and Primary Pain Syndromes, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples, Italy; ²³DMED, University of Udine and Clinical Neurology, Udine University Hospital, Italy; ²⁴Fondazione Policlinico Universitario Campus Bio-Medico, Roma e Università Campus Bio-Medico di Roma, Italy; ²⁵Department of Molecular Pathobiology and Pain Research Center, College of Dentistry, New York University, NY, USA

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15988

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• P037 | ACCELERATED DLPFC-TDCS AS AN ADJUNCTIVE TREATMENT FOR CHRONIC MIGRAINE UNRESPONSIVE TO MONOCLONAL ANTIBODIES: PRELIMINARY FINDINGS FROM A SHAM-CONTROLLED PILOT STUDY

  L. Clemente¹, G. Paparella^1|2, V. Francabandiera³, A. Telesca^3|4, E. Ammendola^1|5, L. Grazzi³, M. de Tommaso¹ | ¹Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience, University of Bari Aldo Moro, Italy; ²IRCCS Neuromed, Pozzilli, Italy; ³Neuroalgology Unit, Department of Clinical Neuroscience, IRCCS Carlo Besta Neurological Institute and Foundation, Milan, Italy; ⁴Neurointensive Care Unit, Department of Neurosurgery, IRCCS Carlo Besta Neurological Institute and Foundation, Milan, Italy; ⁵University Niccolò Cusano, Rome, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15993

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• OC15 | CENTRAL AND PERIPHERAL CONTRIBUTIONS TO FIBROMYALGIA PHENOTYPES: ROLE OF MIGRAINE COMORBIDITY AND SMALL FIBRE PATHOLOGY

  G. Paparella^1|2, E. Ammendola¹, S. Limitone¹, L. Clemente¹, G. Libro¹, M. de Tommaso¹ | ¹Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Italy; ²IRCCS Neuromed, Pozzilli (IS), Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15953

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• OC14 | MIGRAINE IN OLDER ADULTS: A MULTICENTER REAL-WORLD ANALYSIS FROM THE ITALIAN RICE REGISTRY

  G. Paparella^1|2, L. Iannone³, G. Paparella¹, S. Scannicchio¹, C. Abbatantuono¹, L. Clemente¹, M. Delussi⁴, M. de Tommaso¹ | ¹Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Italy; ²IRCCS Neuromed, Pozzilli (IS), Italy; ³Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Italy; ⁴Department of Education, Psychology, Communication (For.Psi.Com.), University of Bari Aldo Moro, Italy

  03-11-2026

  DOI https://doi.org/10.4081/cc.2026.15952

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