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PO-87 | Dual inhibition of FAAH and TRPV1 receptors counteracts nitroglycerin-induced migraine-like symptoms only in male rats Miriam Francavilla,^1,2 Sara Facchetti,^1,2 Chiara Demartini,¹ Anna Maria Zanaboni,^1,2 Michela Palmisani,³ Valentina Franco,³ Rosaria Greco,¹ Cristina Tassorelli^1,2 | ¹Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia; ²Department of Brain and Behavioral Sciences, University of Pavia; ³Department of Internal Medicine and Therapeutics, Clinical and Experimental Pharmacology Unit, University of Pavia, Italy

Società Italiana per lo Studio delle Cefalee (SISC)

06-11-2025

https://doi.org/10.4081/cc.2025.15911

369
PO-84 | Inhibiting the peripheral degradation of anandamide reduces trigeminal hyperalgesia in a model of dural neurogenic inflammation via a CB1/CB2-independent mechanism Chiara Demartini,¹ Rosaria Greco,¹ Miriam Francavilla,^1,2 Sara Facchetti,^1,2 Cristina Tassorelli^1,2 | ¹Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; ²Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy

Società Italiana per lo Studio delle Cefalee (SISC)

06-11-2025

https://doi.org/10.4081/cc.2025.15908

325

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