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PO-87 | Dual inhibition of FAAH and TRPV1 receptors counteracts nitroglycerin-induced migraine-like symptoms only in male rats Miriam Francavilla,1,2 Sara Facchetti,1,2 Chiara Demartini,1 Anna Maria Zanaboni,1,2 Michela Palmisani,3 Valentina Franco,3 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia; 2Department of Brain and Behavioral Sciences, University of Pavia; 3Department of Internal Medicine and Therapeutics, Clinical and Experimental Pharmacology Unit, University of Pavia, Italy
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OC-01 | Evolution of nitroglycerin-triggered premonitory symptoms in participants with migraine Gabriele Sebastianelli,1,2 Catarina Fernandes,1,3 Peter J. Goadsby,1 Nazia Karsan1 | 1NIHR King’s Clinical Research Facility, SLaM Biomedical Research Centre and Wolfson SPaRC, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK; 2Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino ICOT, Sapienza University of Rome, Latina, Italy; 3Neurology Department, Local Health Unit of Coimbra, Portugal
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PO-85 | Alterations in gut microbiota and the endocannabinoid system in an animal model of chronic migraine Sara Facchetti,1,2 Chiara Demartini,1 Miriam Francavilla,1,2 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; 2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy
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OC-16 | Network-level brain connectivity alterations in an animal model of migraine and the effects of olcegepant treatment Rosaria Greco,1 Gloria Castellazzi,1 Miriam Francavilla,1,2 Chiara Demartini,1 Sara Facchetti,1,2 Daniele Martinelli,1 Cristina Tassorelli1,2 | 1Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 2Department of Brain and Behavioral Sciences, University of Pavia, Italy
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