SISC-Poster
Vol. 35 No. S1 (2025): 39° Conference of the Italian Society for the Study of Headaches (SISC)

PO-17 | A clinical guide to assess and manage altered pain sensitivity and cervical musculoskeletal impairments migraine patients. Part 1: Assessment and profiling

Stefano Di Antonio,1,2 Lars Arendt-Nielsen,1 Matteo Castaldo1,3 | 1Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), SMI, School of Medicine, Aalborg University, Aalborg, Denmark; 2Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa; 3Department of Medicine and Surgery, Clinical Psychology, University of Parma, Italy

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Published: 6 November 2025
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Background: Migraine is a complex neurological disorder characterized by different signs and symptoms, and patients often present with an altered pain sensitivity and cervical musculoskeletal impairments1,2. Therefore, in the management of migraine patients the assessment and eventually a specific treatment of these aspects should be included. This abstract provides evidence-based guidance on assessment techniques and clinical reasoning strategies to help clinicians effectively evaluate and interpret these aspects in clinical practice.

Methods: A review of the current literature has been performed and the results reported in this abstract are based on a recently published manuscript1,2. This abstract offers evidence-based guidance on how to perform and interpret assessment tests to effectively evaluate cervical musculoskeletal impairments and altered pain sensitivity in migraine patients.

 Results: This abstract provides a detailed explanation of how to perform a subjective examination (anamnesis) and an objective examination (physical examination): each test is described in detail, along with reference cut-off values that help identify the presence of these impairments. Based on the assessment results, each migraine patient was categorized into a specific subgroup according to the presence of cervical musculoskeletal impairments and/or altered pain sensitivity.

Conclusion: The ability to accurately assess increased pain sensitivity and cervical musculoskeletal impairments will enable clinicians to profile migraine patients based on these characteristics and implement a personalized treatment approach.

References

1.  Castaldo M, Arendt-Nielsen L, Di Antonio S. A clinical guide for physiotherapists to assess and manage cervical musculoskeletal impairment and pain sensitivity in migraine patients. J Man Manip Ther. 2025 May 18:1-18. 
2. Di Antonio S, Arendt-Nielsen L, Castaldo M. Cervical musculoskeletal impairments and pain sensitivity in migraine patients. Musculoskelet Sci Pract. 2023 Aug;66:102817.

 

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Citations

1. Castaldo M, Arendt-Nielsen L, Di Antonio S. A clinical guide for physiotherapists to assess and manage cervical musculoskeletal impairment and pain sensitivity in migraine patients. J Man Manip Ther. 2025 May 18:1-18.
2. Di Antonio S, Arendt-Nielsen L, Castaldo M. Cervical musculoskeletal impairments and pain sensitivity in migraine patients. Musculoskelet Sci Pract. 2023 Aug;66:102817. DOI: https://doi.org/10.1016/j.msksp.2023.102817

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1.
PO-17 | A clinical guide to assess and manage altered pain sensitivity and cervical musculoskeletal impairments migraine patients. Part 1: Assessment and profiling: Stefano Di Antonio,1,2 Lars Arendt-Nielsen,1 Matteo Castaldo1,3 | 1Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), SMI, School of Medicine, Aalborg University, Aalborg, Denmark; 2Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa; 3Department of Medicine and Surgery, Clinical Psychology, University of Parma, Italy. Confinia Cephalal [Internet]. 2025 Nov. 6 [cited 2026 May 25];35(S1). Available from: https://www.confiniacephalalgica.com/site/article/view/15838