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PO-85 | Alterations in gut microbiota and the endocannabinoid system in an animal model of chronic migraine Sara Facchetti,1,2 Chiara Demartini,1 Miriam Francavilla,1,2 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; 2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy
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PO-52 | Long-term efficacy of CGRP mAbs: new insights and current evidence Oreste Marsico,1 Marta Lioi,2 Rosario Iannacchero,3 Michele Trimboli3 | 1Department of Neuroscience, “Giovanni Paolo II” Hospital, Lamezia Terme, Catanzaro, Italy; 2Department of Neurology, Magna Graecia University, Catanzaro, Italy; 3Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-20 | Phenotypic description of a multigenerational family with PRRT2 gene mutation: a case series of six members affected by hemiplegic migraine and paroxysmal events Fabiana Cerulli,1 Costanza Sottani,1 Giulia Di Lazzaro,1,2 Paolo Calabresi,1,2 Anna Rita Bentivoglio,1,2 Catello Vollono1,3 | 1Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Rome; 2UOC Neurologia, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy; 3Neurofisiopatologia, Dipartimento di Scienze dell'invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy
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OC-12 | The potential role of sleep quality in the relationship between glymphatic function and migraine frequency: insights from a cross-sectional study Maria Grazia Vittorini, Raffaele Ornello, Federico Salfi, Antonio Innocenzi, Federico De Santis, Federico Bruno, Francesca Pistoia, Michele Ferrara, Alessandra Splendiani, Simona Sacco | Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy
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PO-72 | Stigma in migraine: preliminary results from the “Studio Emicrania Maugeri” Project Luca Giani, Christian Lunetta | Istituti Clinici Scientifici Maugeri IRCCS, Neurological Rehabilitation Unit of Milano Institute, Milan, Italy
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PO-39 | Leeds Dependence Questionnaire (LDQ) in migraine: diagnostic utility without predictive value for anti-CGRP (R) response Antonio Munafò,1 Andrea Burgalassi,1 Giulia Vigani,2 Francesco De Cesaris,1 Alberto Chiarugi1,2 | 1Headache Center and Clinical Pharmacology Unit, Careggi University Hospital, Florence, Italy; 2Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy
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PO-07 | Psychological management of children treated at the Pediatric Headache Centre of Turin: preliminary analysis Emanuela Serri, Annachiara Lamberti Zanardi, Raffaella Mascolo, Barbara Lauria, Roberta Rossi, Sara Simona Racalbuto, Antonia Versace, Claudia Bondone | Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin, Italy
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PO-92 QZU® (Kudzu e.s.: 200 mg of which Isoflavones: 80 mg and Puerarin: 60 mg; ComplexZyme vegan®: 40 mg) in the prophylaxys of migraine without aura: a retrospective observational study Ennio Pucci,1 Ludovica Pucci,2 Alberto Vercesi3 | 1Department of Nervous System and Behavioral Sciences, University of Pavia; 2Nutritional biologist, Master in Nutritional and Clinical Dietetics, University of Pavia, Italy; 3Scientific Advisor
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PO-58 | Pilot protocol to improve the booking and management network for chronic headache in secondary and tertiary care services A. Granato,1 L. Bartole,1 S. Centonze,2 A. Lodi,3 M. Lodi Zollia,3 P. Manganotti1 | 1Clinical Unit of Neurology, Headache Centre, Department of Medicine, Surgery and Health Sciences, ASUGI, University of Trieste, Trieste, Italy; 2Research & Innovation Unit, ASUGI, University of Trieste, Trieste, Italy; 3Funzione Organizzativa, Gestione Offerte Ambulatoriali, ASUGI, University of Trieste, Trieste, Italy
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PO-26 | Optic nerve sheath ultrasound in idiopatic intracranial hypertension: early findings Francesca Cotichelli,1,2 Davide Mascarella1,1,2 Valentina Favoni,1 Gaia Patanè,1,2 Francesco Severi,1,2 Francesca Verna,1,2 Giulia Pierangeli,1,2 Sabina Cevoli1 | 1IRCCS Istituto delle Scienze Neurologiche di Bologna; 2DIBINEM, Department of Biomedical and Neuromotor Science, Alma Mater Studiorum, Bologna, Italy
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OC-18 | Effectiveness of fremanezumab up to 12 months in different subgroups of participants: results from the Italian analysis of the PEARL study Raffaele Ornello,1 Gisella Airola,2 Letizia Curto,3 Diletta Alivernini,4 Chiara Abagnale,5 Pinar Kokturk,6 Yan Tereshko7 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Surgical Sciences, Women's Headache Center, University of Turin; 3Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa; 4Department of Neuroscience, Mental Health and Sensory Organs (NESMOS), Sapienza University of Rome; 5Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino ICOT, Latina, Italy; 6TEVA Pharmaceuticals Europe B.V., Haarlem, The Netherlands; 7Clinical Neurology, Department of Head-Neck and Neuroscience, Azienda Sanitaria Universitaria Friuli Centrale (ASU FC), Udine, Italy
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PO-78 | No changes in blood pressure assessed with the 24-hour Holter monitoring in patients treated with anti-CGRP monoclonal antibodies: a prospective observational study (SAFHYPER) Flavia Lo Castro,1 Niccolò Bonini,2 Luigi Francesco Iannone,1,3 Alberto Boccalini,1 Daria Brovia,1 Luca Pani,1,3 Giuseppe Boriani,2,3 Simona Guerzoni1 | 1Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico di Modena, Modena, Italy; 2Cardiology Division, AOU Policlinico di Modena, Modena, Italy; 3Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy
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PO-45 | Botulinum toxin in clinical practice: a turning point for chronic migraine and MOH Chiara Zilli, Davide Chiffi, Giada Giuliani, Francesca Traccitto, Mariangela Fratino, Marta Altieri | Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy
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PO-13 | HD-EEG Delta connectivity rapidly alters after one month of atogepant in migraine patients Maria Albanese,1,2 Matteo Conti,1 Silvio Bagetta,1 Federico Carparelli,2 Vittoria Carla D’Agostino,2 Fabio Placidi,1,2 Alessandro Stefani,1,2 Nicola Biagio Mercuri,1-3 | 1Department of Systems Medicine, University of Rome Tor Vergata, Rome; 2Neurology Unit, Tor Vergata University Hospital, Rome; 3IRCCS Santa Lucia Foundation, Rome, Italy
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OC-05 | Mid-term effectiveness and tolerability of atogepant in the prevention of migraine: a real life, prospective, multicentric study (the STAR study) Fabrizio Vernieri,1 Luigi Francesco Iannone,2,3 Gabriele Sebastianelli,4 Flavia Lo Castro,2, Federico De Santis,5 Michele Corrado,6 Marilena Marcosano,1 Raffaele Ornello,5 Licia Grazzi,7 Danilo Antonio Montisano,7 Francesco De Cesaris,8 Antonio Munafò,8 Gianluca Avino,9 Michele Trimboli,10 Maria Albanese,11 Antonio Russo,12 Giorgio Dalla Volta,13 Marina Romozzi,14 Paola Merlo,15 Maria Pia Prudenzano,16 Maria Rosaria Valente,17 Innocenzo Rainero,18 Giada Giuliani,19 Luisa Fofi,1 Alberto Doretti,20 Gloria Vaghi,6 Francesca Pistoia,5 Delfina Ferrandi,21 Stefania Battistini,22 Simona Sacco,5 Simona Guerzoni,2 Claudia Altamura1 on behalf of the Italian Headache Registry (RICe) Study Group | 1Fondazione Policlinico Campus Bio-Medico, Roma; 2AOU Policlinico di Modena; 3Università di Modena e Reggio Emilia. 4Sapienza University of Rome Polo Pontino, Latina; 5University of L’Aquila; 6University of Pavia, Pavia, Italy and IRCCS Mondino Foundation, Pavia; 7IRCCS Istituto Neurologico Carlo Besta, Milano; 8AOU Careggi, Firenze; 9SOC Neurologia, Ospedale di Prato, Prato; 10Azienda Ospedaliera-universitaria "Renato Dulbecco", Catanzaro; 11Università Roma Tor Vergata, Roma; 12Università della Campania "Luigi Vanvitelli", Napoli; 13U.O Neurologia, Istituto Clinico Città di Brescia, Gruppo San Donato, Brescia; 14Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma; 15UO di Neurologia, Humanitas Gavazzeni, Bergamo; 16Clinica Neurologica "L. Amaducci", Azienda Ospedaliero-Universitaria Consorziale di Bari; 17Dipartimento di Neuroscienze, Azienda Sanitaria Universitaria Integrata di Udine; 18Dipartimento di Neuroscienze, Città della Salute e della Scienza di Torino; 19Centro per la diagnosi e terapia delle cefalee, Policlinico Umberto I, Roma; 20IRCCS Istituto Auxologico Italiano, Milano; 21AOU Alessandria; 22University of Siena, Siena, Italy
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PO-65 | The complexity of chronic headache: towards tailored therapies through a multidimensional assessment Silvia Favaretto,1 Giulia Demo,2 Veronica Rizzato,2 Elisabetta Patron,2,3,4 Sara Bianconi,2 Stèphanie Maldera,2 Giulia Buodo,2,3 | 1UOC Clinica Neurologica, Azienda Ospedale-Università Padova, Padua, Italy; 2Centro di Ateneo Servizi Clinici Universitari Psicologici (SCUP), University of Padua, Italy; 3Department of General Psychology, University of Padua, Padova, Italy; 4Padua Neuroscience Center (PNC), University of Padua, Padova, Italy
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PO-32 | Post-traumatic painful trigeminal neuropathy (13.1.2.3 - ICHD-3) following misguided gamma knife surgery: a case of diagnostic oversight with lasting consequences Marta Lioi,1 Laura Marino,1 Michele Trimboli2 | 1Department of Neurology, Magna Graecia University, Catanzaro, Italy; 2Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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OC-24 | A retrospective case-control study aimed at analyzing, through the administration of a questionnaire, the prevalence, clinical features and the risk factors for chronicity in a sample of 419 pediatric patients Alice Bonuccelli, Sara Mundo, Emma Iacopelli, Alessandro Orsini, Lorenza Marini, Diego Peroni | Neuropediatric, Pediatric Clinic, AOU Pisa, Italy
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PO-84 | Inhibiting the peripheral degradation of anandamide reduces trigeminal hyperalgesia in a model of dural neurogenic inflammation via a CB1/CB2-independent mechanism Chiara Demartini,1 Rosaria Greco,1 Miriam Francavilla,1,2 Sara Facchetti,1,2 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; 2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy
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PO-51 | Rimegepant combined with valproic acid and botulinum toxin in refractory hemiplegic migraine: a case report Gianni Difonzo, Cinzia Tamborino, Adriana Fallacara, Damiano Paolicelli, Maria Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy
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PO-19 | Unraveling the spectrum of migraine resistant to treatments: searching for novel biological PHEnotypes and theRApeutic approaches (SPHERA project) M. Giraudo,1,2 R. De Icco,1,2 G. Vaghi,1,2 V. Grillo,1,2 F. Bighiani,1,2 M. Corrado,2 A. Antoniazzi,1,2 F. Cammarota,1,2 B. Agostini,1,2 A. Solfrizzi,1,2 M. Allena,2 E. Guaschino,2 N. Ghiotto,2 R. Greco,2 C. Demartini,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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OC-11 | Corneal nerve plexus impairment in patients with trigeminal neuralgia Daniel Litewczuk,1 Gianfranco De Stefano,1 Sabrina Compagno,2 Mattia D’Andrea,2 Ludovico Alisi,2 Marco Marenco,2 Giulia Di Stefano,1 Andrea Truini1 | 1Department of Human Neuroscience, Sapienza University of Rome, 2Department of Sense Organs, Sapienza University of Rome, Italy
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PO-71 | Is Doctor Google retiring? How Generative Artificial Intelligence is transforming the perception and management of headaches Matteo Bellamio,1 Sofia Zywicki,1 Rocco Quatrale,2 Giorgio Zanchin,3 Ferdinando Maggioni,3 Alberto Terrin1 | 1Centro Cefalee dell’Angelo, Neurology, Ospedale dell'Angelo, AULSS3 Serenissima, Mestre (VE), Italy; 2Neurology, Ospedale dell'Angelo, AULSS3 Serenissima, Mestre (VE), Italy; 3Neurology, University of Padua, Padua, Italy
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PO-38 | Impact of atogepant on achieving best possible quality of life among patient global impression of change responders Cristina Tassorelli,1 Pranav Gandhi,2 Molly Duan,2 Karen Carr,2 Kandavadivu Umashankar,2 Jonathan Stokes,2 Grace Forde,3 Tanya Bilchik,4 Martina Martini*, Rashmi Halker Singh5 | 1University of Pavia, Pavia, Italy; 2AbbVie, North Chicago, IL, USA; 3North American Partners in Pain Management, North New Hyde Park, NY, USA; 4Department of Neurology, Yale School of Medicine, New Haven, CT, USA; 5Mayo Clinic, Phoenix, AZ, USA *Abbvie Srl, Rome, Italy.
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PO-06 | Children’s headache through drawings: a narrative review and a portrait gallery Floriana Ferro,1,2 Caterina Gaspari,1,2 Giulia Manfrè,1,2 Federica Cernigliaro,1 Daniela D’Agnano,3 Ruben Panzica,4 Edvige Correnti,2 Maria Rosita Ruta,5 Francesca Marchese,5 Renata Pitino,2 Maria Rita Capizzi,2 Giuseppe Santangelo,2 Antonella Versace,6 Vittorio Sciruicchio,3 Vincenzo Raieli2 | 1Child Neuropsychiatry Unit Department, Pro.MI.S.E. "G. D'Alessandro", University of Palermo; 2Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo; 3Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari, Bari; 4Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Messina; 5Child Neuropsychiatry Unit, ASP 6, Palermo; 6Pediatric Headache Center, Pediatric Emergency Dept, Regina Margherita Children's Hospital, Turin, Italy
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PO-91 | Real-world evidence of CGRP dual blockade: clinical and biomarker insights from combined therapy in chronic migraine Laura Marino,1 Marta Lioi1, Rosario Iannacchero,2 Michele Trimboli2 | 1Department of Neurology, Magna Graecia University, Catanzaro; 2Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-57 | Early treatment with atogepant improves sleep quality without sleep-related adverse events: a prospective observational study Alberto Boccalini,1 Luigi Francesco Iannone,1,2* Flavia Lo Castro,1 Daria Brovia,1 Marina Romozzi,3,4 Fabrizio Vernieri,5,6 Claudia Altamura,5,6 Simona Guerzoni1 | 1Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico di Modena, Modena, Italy; 2Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy; 3Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Rome, Italy; 4Neurologia, Dipartimento di neuroscienze, Organi di Senso e Torace, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 5Headache Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Italy; 6Università Campus Bio-Medico di Roma, Italy
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PO-25 | Antiepileptic medication in PRRT2 familial hemiplegic migraine: a case report L. Bartole, A. Granato, G. Garascia, P. Manganotti | Clinical Unit of Neurology, Headache Centre, Department of Medicine, Surgery and Health Sciences, University of Trieste, Italy
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OC-17 | Profiling miR-30a expression in patients with episodic and chronic migraine Elisa Rubino,1,2 Elisa Maria Piella,1 Giulia Cicilese,1,3 Silvia Boschi,1 Alberto Mario Chiarandon,1 Elena Tamagno,1,3 Michela Guglielmotto,1,3 Innocenzo Rainero1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Headache Center, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino; 3Neuroscience Institute Cavalieri Ottolenghi (NICO), Orbassano (TO), Italy
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PO-77 | Real-world evidence of Atogepant efficacy in patients unresponsive to anti-CGRP monoclonals Matteo Cortinovis, Marco Bolchini, Paola Zavarise, Giulia Campana, Giorgio Dalla Volta | Headache Center, Istituto Clinico Città di Brescia, Gruppo San Donato, Brescia, Italy
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PO-44 | Effectiveness of fremanezumab as preventive treatment of migraine up to 24 months: response rates from the Italian analysis of the PEARL study Alberto Doretti,1 Anna Ambrosini,2 Simone Braca,3 Florindo D’Onofrio,4 Elisa Maria Piella,5 Pinar Kokturk,6 Rosario Iannacchero7 | 1Department of Neurology-Laboratory of Neuroscience, IRCCS, Istituto Auxologico Italiano, Milan, Italy; 2Mediterranean Neurological Institute NEUROMED IRCCS, Pozzilli (IS), Italy; 3Headache Centre, University of Naples “Federico II”, Naples, Italy; 4UOSD Stroke Unit, S.G. Moscati Hospital, Avellino, Italy; 5Neurosciences Department, University of Turin, Turin, Italy; 6Teva Netherlands B.V., Haarlem, The Netherlands; 7Department of Neurology, Headache Center, Regional Hospital “Pugliese-Ciaccio”, Catanzaro, Italy
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PO-12 | The long-term efficacy on migraine of non-ketogenic low-carb diet after treatment with ketogenic diet Silvia Favaretto,1 Francesco Francini Pesenti2 | 1Headache centre, Neurology Unit, Department of Neuroscience, University Hospital of Padua; 2Department of Medicine (DIMED), Clinical Nutrition, University Hospital of Padua, Italy
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OC-04 | The chronopharmacology of atogepant in migraine prevention: a real-world evaluation of influence of timing of administration on effectiveness and tolerability Luigi Francesco Iannone,1,2 Gabriele Sebastianelli,3 Flavia Lo Castro,2 Federico De Santis,4 Michele Corrado,5 Marilena Marcosano,6,7 Raffaele Ornello,4 Licia Grazzi,8 Danilo Antonio Montisano,8 Francesco De Cesaris,9 Antonio Munafò,9 Gianluca Avino,10 Michele Trimboli,11 Maria Albanese,12 Antonio Russo,13 Giorgio Dalla Volta,14 Marina Romozzi,15 Paola Merlo,16 Luisa Fofi,6,7 Alberto Doretti,17 Gloria Vaghi,5 Francesca Pistoia,4 Delfina Ferrandi,18 Stefania Battistini,19 Gianluca Coppola,3 Simona Sacco,4 Simona Guerzoni,2 Claudia Altamura,6,7 Fabrizio Vernieri,6,7 On behalf of the Italian Headache Registry (RICe) Study Group | 1Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia; 2Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico di Modena; 3Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina; 4Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 5Department of Brain and Behavioral Sciences, University of Pavia; Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 6Headache Unit, Fondazione Policlinico Universitario Campus Bio-Medico, Roma; 7Neurology Unit, Università Campus Bio-Medico di Roma; 8Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan; 9Headache center and Clinical Pharmacology, AOU Careggi, Florence; 10SOC Neurologia, Ospedale di Prato; 11Azienda Ospedaliera-universitaria "Renato Dulbecco", Catanzaro; 12Università Roma Tor Vergata, Roma; 13Università della Campania "Luigi Vanvitelli", Napoli; 14U.O Neurologia, Istituto Clinico Città di Brescia, Gruppo San Donato, Brescia; 15Fondazione Policlinico Universitario A. Gemelli IRCCS, Università Cattolica del Sacro Cuore, Roma, Italy; 16UO di Neurologia, Humanitas Gavazzeni, Bergamo; 17Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milano; 18Neurology Department, Azienda Ospedaliero Universitaria, Santi Antonio e Biagio e Cesare Arrigo, Alessandria; 19Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy
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PO-64 | Telemedicine in a second level headache clinic of Azienda Sanitaria Locale Roma 1: a lesson learned from the SarsCov2 pandemic Teresa Catarci | ASL Roma 1, Rome, Italy
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PO-31 | Could lamotrigine represent an effective treatment strategy in patients with migraine with aura? An observational study M. Marziani, M. Silvestro, I. Orologio, L. Tartaglione, F.M. Chianese, A. Tessitore, A. Russo | Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Italy
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OC-23 | The REPICEF Project: a school-based epidemiological study on primary headaches in children and adolescents Agnese Onofri,1 Chiara Rosignoli,1 Vittorio Trozzi,1 Martina D’Ambrosio,1 Benedetta Germani,1 Roberta Ciuffini,2 Raffaele Ornello,1 Simona Sacco1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Clinical Medicine, Public health, Life and Environmental Sciences University of L’Aquila, Italy
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PO-83 | Serum diamine oxidase activity in patients with cluster headache: a cross-sectional case–control study Silvia Boschi,1 Elisa Maria Piella,1 Tilde Manetta,3 Paola Merlach,3 Alberto Mario Chiarandon,1 Alessia Agostinelli,1 Barbara Donati Morello,3 Giulio Mengozzi,3 Innocenzo Rainero,1,2 Elisa Rubino,1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Headache Center, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Turin, Italy; 3Department of Laboratory Medicine, Città della Salute e della Scienza University Hospital, Turin, Italy
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PO-50 | Enhanced integration and synergy in EEG- and fNIRS-based networks in migraine patients following three-month galcanezumab treatment: associations with long-term clinical effects Giulia Paparella,1,2 Marianna La Rocca,3 Livio Clemente,1 Emmanuella Ladisa,1 Chiara Abbatantuono,1 Elena Ammendola,1 Marianna Diletta Delussi,4 Katia Ricci,1 Giusy Tancredi,1 Antonio Lacalamita,3 Alfonso Monaco,3 Nicola Amoroso,5 Sebastiano Stramaglia,3 Roberto Bellotti,3 Marina de Tommaso1 | 1Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Bari, Italy; 2IRCCS Neuromed, Pozzilli (IS), Italy; 3Interateneo Department of Physics "M. Merlin", University of Bari Aldo Moro, Bari, Italy; 4Department of Education, Psychology, Communication (For.Psi.Com.), University of Bari Aldo Moro, Bari, Italy; 5Department of Pharmacy–Drug Sciences, University of Bari Aldo Moro, Bari, Italy
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PO-18 | A clinical guide to assess and manage altered pain sensitivity and cervical musculoskeletal impairments migraine patients. Part 2: individualised treatment Matteo Castaldo,1,2 Lars Arendt-Nielsen,1 Stefano Di Antonio1,3 | 1Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), SMI, School of Medicine, Aalborg University, Aalborg, Denmark; 2Department of Medicine and Surgery, Clinical Psychology, University of Parma; 3Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa, Italy
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OC-10 | Assessing white matter hyperintensities in cluster headache: a distinct pathophysiological profile compared to migraine G. Giuliani,1 A. Viganò,2 C. Zilli,1 D. Chiffi,1 E. Vicenzini,1 V. Di Piero,1 M. Altieri1 | 1Department of Human Neuroscience, Sapienza University of Rome; 2IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
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PO-70 | A nomogram for the prediction of response to anti-CGRP mAbs: the CGRP score Marina Romozzi,1 Ammar Lokhandwala,2 Catello Vollono,1 David García-Azorín,3 Giulia Vigani,4 Francesco De Cesaris,4 Claudia Altamura,5 Fabrizio Vernieri,5 Paolo Calabresi,1 Sonia Di Tella,6 Luigi Francesco Iannone7 1Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome, Italy; 2Drexel University, Philadelphia, PA, USA; 3Hospital Universitario del Río Hortega, Valladolid, Headache Unit, Department of Neurology, Valladolid, Spain; 4Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy; 5 Neurologia, Dipartimento di Medicina e Chirurgia, Università Campus Bio-Medico di Roma, Rome, Italy; 6Dipartimento di Psicologia, Università Cattolica del Sacro Cuore, Milan, Italy; 7Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy
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PO-37 | Trigeminal autonomic cephalalgia as the initial presentation of a cerebral cavernous malformation: a rare case report Francesco Maurizio Chianese, Marcello Silvestro, Ilaria Orologio, Lorenzo Tartaglione, Marcella Marziani, Antonio Russo | Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy
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PO-05 | Validation of the Italian version of the HARDSHIP Questionnaire in a school-based population Agnese Onofri,1 Chiara Rosignoli,1 Vittorio Trozzi,1 Martina D’Ambrosio,1 Benedetta Germani,1 Roberta Ciuffini,2 Raffaele Ornello,1 Simona Sacco1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Clinical Medicine, Public health, Life and Environmental Sciences, University of L’Aquila, Italy
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PO-90 | CAPSULASE® (PEA (palmitoylethanolamide), PHYTOSOME (quercetin from Sophora japonica L. 40% soy lecithin, microcrystalline cellulose, aerosil), CASPEROME (Boswellia serrata R., gum resin 40%, soy lecithin, microcrystalline cellulose, aerosil), bromelain 2 Ennio Pucci,1 Ludovica Pucci,2 Alberto Vercesio3 | 1Department of Nervous System and Behavioral Sciences, University of Pavia; 2Nutritional biologist, Master in Nutritional and Clinical Dietetics, University of Pavia, Italy; 3Scientific Advisor
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PO-56 | The role of bilateral greater occipital nerve block in resistant chronic migraine with medication overuse Leonardo Troilo, Letizia Curto, Giulia Procopio, Antonia Di Chirico, Gabriele Siciliano, Sara Gori, Filippo Baldacci | Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa-AOUP, Pisa, Italy
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