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PO-68 | Bipolar disorder spectrum and psychopathology in cluster headache compared to migraine: a cross-sectional study in a hospital headache clinic Isabella Getuli, Giada Giuliani, Chiara Zilli, Simone Preti, Gaia Chiecchi, Lorenzo Tarsitani, Marta Altieri | Dipartimento di Neuroscienze Umane, Sapienza Università di Roma, Italy
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PO-35 | Treatment of chronic and episodic migraine with atogepant improves quality of life in patients with comorbid multiple sclerosis: the experience of the Headache Center at Spaziani Hospital, Frosinone Laura Borrello; Fabiana Marinelli; Maria Lorena Marziale; Ilaria Avallone; Fulvio Ferrante; Roberto De Simone | Neurology Unit, Headache Center, Multiple Sclerosis Center, UOC Pharmacy, Spaziani Hospital, Frosinone (FR), Italy
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PO-03 | Intracranial incidental findings on brain magnetic resonance imaging (MRI) in a pediatric population with primary headache: our experience and management Fabiana Ursitti,1 Filippo Tripodi,1 Laura Papetti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Samuela Tarantino,1 Martina Proietti Checchi,1 Massimiliano Valeriani1-3 | 1Developmental Neurology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy; 2Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Department of Health Science and Technology, School of Medicine, Aalborg University, Aalborg, Denmark
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PO-88 | Can tamoxifen and metformin nullify efficacy of CGRP-mAbs migraine prophylaxis? Patrizia Rossi,1,2 Valentina Cima,2 Alessandro Burlina2 | 1Headache Center, 2Neurology Department, San Bassiano Hospital, Bassano del Grappa (VI), Italy
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PO-54 | Patient perspectives on physiotherapy interventions for migraine: a pre- and post-intervention qualitative study Zhiqi Liang,1 Caitlin Scott,1 Felix Cabrera Manrique,1 Sumin Kim,1 Chun Shun Lee,1 Bixiang Cheng,1 Chun Yiu Kwok,1 Matteo Castaldo2 | 1University of Queensland; 2Parma University, Italy
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PO-22 | Impact of sleep disorders on anti-CGRP monoclonal antibodies treatment response in migraine: a cross-sectional study Costanza Sottani,1 Valerio Brunetti,1,2 Fabiana Cerulli,1 Claudia Garattini,4 Gianluca Avino,5 Paolo Calabresi,1,3 Catello Vollono1,4 | 1Università Cattolica del Sacro Cuore, Dipartimento di Neuroscienze, Rome; 2Stroke Unit, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 3UOC Neurologia, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 4UOC Neurofisiopatologia, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 5Unità di Neurologia, Ospedale Santo Stefano, Prato, Italy
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OC-14 | Efficacy of eptinezumab during a migraine attack: preliminary data from an Italian multicenter real-world experience (the BEFREE study) Luisa Fofi,1 Claudia Altamura,1 Marilena Marcosano,1 Alberto Doretti,2 Francesca Pistoia,3 Antonio Granato,4 Simona Guerzoni,5 Michele Trimboli,6 Licia Grazzi,7 Danilo Antonio Montisano,7 Gianluca Avino,8 Gabriele Sebastianelli,9 Carla Fasano,10 Elisa Maria Piella,11 Nicoletta Brunelli,1 Luigi Francesco Iannone,5,12 Fabrizio Vernieri1 on behalf of the Italian Headache Registry (RICe) Study Group | 1Neurosonology and Headache Unit, Fondazione Policlinico Campus Bio-Medico, Rome; 2IRCCS Istituto Auxologico Italiano - Department of Neurology and Laboratory of Neuroscience - Milan; 3University of L’Aquila; 4Headache Center, Neurology Clinic, University of Trieste, University Hospital of Trieste; 5AOU Policlinico di Modena; 6Azienda Ospedaliera-universitaria "Renato Dulbecco", Catanzaro; 7Headache Center, Neuroalgology Dpt, IRCCS Foundation "Carlo Besta" Neurological Institute, Milan; 8SOC Neurologia, Ospedale Santo Stefano, USL Toscana Centro, Prato; 9La Sapienza University of Rome Polo Pontino, Latina; 10Headache and Cerebrovascular Diseases Center, Neurology Unit 2, Careggi University Hospital, Florence; 11Department of Neuroscience “Rita Levi Montalcini”, University of Turin; 12Università di Modena e Reggio Emilia, Italy
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PO-74 | Effectiveness of auricular acupuncture in the management of menstrual migraine: a pilot study Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-41 | Eptinezumab for difficult-to-treat migraine: who responds and who needs more Alessandro Visentini,1,2,3 Roberta Messina,1,2,3 Ilaria Cetta,1,2,3 Edorardo Ratto,1 Laura Zanandrea,1,3 Federica Genovese,1,2,3 Irene Chinali,1 Bruno Colombo,1 Massimo Filippi1,2,3 | 1Neurology Unit and 2Neuroimaging Research Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3Vita-Salute San Raffaele University, Milan, Italy
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PO-09 | When migraine turns severe: a case of aura that lasts too long Alessandra Fera,1 Erica Agosto,1 Giulia Grasso,2 Cristina Vassia,2 Francesca Feyles,2 Carlotta Canavese,3 Sara Racalbuto,2 Antonia Versace2 | 1Department of Public Health and Pediatrics, University of Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin; 3Department of Child Pathology and Care “Regina Margherita”, SSD Pediatric Neurology, Regina Margherita Children’s Hospital, Turin, Italy
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OC-01 | Evolution of nitroglycerin-triggered premonitory symptoms in participants with migraine Gabriele Sebastianelli,1,2 Catarina Fernandes,1,3 Peter J. Goadsby,1 Nazia Karsan1 | 1NIHR King’s Clinical Research Facility, SLaM Biomedical Research Centre and Wolfson SPaRC, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK; 2Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino ICOT, Sapienza University of Rome, Latina, Italy; 3Neurology Department, Local Health Unit of Coimbra, Portugal
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PO-60 | Effectiveness of aerobic exercise, Mulligan technique, and myofascial release in migraine management: preliminary data from a randomized controlled trial Marco Bravi,1,2 Fabio Santacaterina,1,2 Federica Bressi,1,2 Francesca Nasto,1,2 Claudia Altamura,1,2 Fabrizio Vernieri1,2 | 1Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Rome, Italy; 2Università Campus Bio-Medico di Roma, Rome, Italy
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PO-28 | Sex differences in the response to rimegepant for the treatment of acute migraine attacks – insights from the multicenter GAINER study Raffaele Ornello,1 Gloria Vaghi,2,3 Gabriele Sebastianelli,4 Francesco Casillo,4 Antonio Russo,5 Marcello Silvestro,5 Francesca Pistoia,1 Giorgio Dalla Volta,6 Matteo Cortinovis,6 Alberto Chiarugi,7 Danilo Antonio Montisano,8 Licia Grazzi,8 Maria Pia Prudenzano,9 Sabina Cevoli,10 Edoardo Mampreso,11 Gianluca Avino,12 Marina Romozzi,13 Mariarosaria Valente,14 Carla Fasano,15 Stefania Battistini,16 Antonio Granato,17 Elisa Maria Piella,18 Innocenzo Rainero,18 Federico De Santis,1 Simona Sacco,1 Maria Albanese,19 Michele Trimboli,20 Alberto Doretti,21 Cristina Tassorelli,2,3 Luigi Francesco Iannone,22 Roberto De Icco2,3 on behalf of the Italian Headache Registry (RICe) Study Group | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Brain and Behavioral Sciences, University of Pavia; 3Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 4Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina; 5Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples; 6Headache Center of Clinical Neurology of Istituto Clinico "Città di Brescia", Brescia; 7Department of Health Sciences, University of Florence; 8Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan; 9Headache Center, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari; 10IRCCS Istituto Di Scienze Neurologiche di Bologna, Programma Cefalee e Algie Facciali, Bologna; 11Headache Centre, Neurology - Euganea, Health Unit, Padua; 12Neurology Unit, Ospedale Santo Stefano, USL Toscana Centro, Prato; 13Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome; 14Clinical Neurology, Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero Santa Maria della Misericordia, Udine; 15Headache and Facial Pain Center Neurology, AOU Careggi, Florence; 16Department of Medical, Surgical and Neurological Sciences, University of Siena; 17Headache Centre, Clinical Unit of Neurology, School of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, ASUGI, University of Trieste; 18Department of Neurosciences “Rita Levi Montalcini”, University of Turin; 19Department of Systems Medicine, University of Rome Tor Vergata, Rome; 20University Magna Graecia, Catanzaro; 21Department of Neuroscience - Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan; 22University of Modena and Reggio Emilia, Modena, Italy
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OC-20 | The inflammatory burden index in pediatric migraine: a clinical study Carola Meo¹, Giulia Manfrè¹, Antonella Morea², Caterina Gaspari¹, Martina Tarantini², Maria Rosita Ruta³, Sofia D’Agostino¹, Edvige Correnti⁴, Daniela D’Agnano², Diletta Lopes⁴, Rosaria Nardello¹, Giuseppe Santangelo⁴, Vittorio Sciruicchio², Vincenzo Raieli⁴ | 1Child Neuropsychiatry Unit Department, Pro.M.I.S.E. "G. D'Alessandro", University of Palermo; 2Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari; 3Child Neuropsychiatry Unit, ASP 6 Palermo; 4Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo, Italy
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PO-80 | Real-world effectiveness of atogepant for the preventive treatment of migraine in a cohort of multi -refractory patients: a single center study M. De Luca,1 L. Ferraù,1 A. Cafarchio,2 M.S. Adragna,1 M. Autunno1 | 1Unit of Neurology and Neuromuscular Diseases, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy; 2Department of Medicine and Health Sciences “Vincenzo Tibero” DIMES, University of Molise, Campobasso, Italy
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PO-47 | Systemic ozone treatment in chronic migraine: a focus on disability reduction and medication use Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-15 | Disclosing somatosensory system alterations in trigeminal neuralgia Gianfranco De Stefano, Daniel Litewczuk, Enrico Evangelisti, Giuseppe Di Pietro, Pietro Falco, Eleonora Galosi, Caterina Leone, Francesca Caramia, Andrea Truini, Giulia Di Stefano | Department of Human Neuroscience, Sapienza University of Rome, Italy
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OC-07 | A retrospective analysis of headache and CADASIL association Danilo Antonio Montisano,1 Giulia Regonesi,1 Licia Grazzi,1 Alessandra Parisi,1 Alberto Raggi,2 Elisabetta Soldini,2 Giorgia Camarda,2 Matilde Leonardi,2 I. Canavero,3 E.M. Zacarias,3 Anna Bersano,3 Nicola Rifino3 | Fondazione IRCCS Istituto Neurologico Carlo Besta: 1SSD Centro Cefalee; 2SC Neurologia Salute Pubblica e Disabilità, 3SC Malattie Cerebrovascolari, Milan, Italy
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PO-67 | Investigating plasma neurofilament light chain levels in patients with migraine: a cross-sectional study Elisa Maria Piella,1 Alberto Mario Chiarandon,1 Silvia Boschi,1 Fausto Roveta,1 Lucrezia Bonino,1 Giulia Gioiello,2 Giulia Montesano,2 Giulio Mengozzi,2 Innocenzo Rainero,1,3 Elisa Rubino1,3 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Clinical Biochemistry Laboratory “Baldi e Riberi”, A.O.U. Città della Salute e della Scienza di Torino, Turin, Italy; 3Headache Center, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Turin, Italy
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PO-34 | Febrile headache in an immunosuppressed patient with autoimmune disease: a probable case of neurosarcoidosis Giulia Settembrini, Giovanni Rinaldi, Marco Alabiso, Ilenia Corbelli, Paola Sarchielli | Clinica Neurologica, Ospedale Santa Maria della Misericordia, Università degli Studi di Perugia, Italy
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PO-02 | Migraine in youth: a double challenge to cognition and emotion Samuela Tarantino,1 Martina Proietti Checchi,1 Laura Papetti,1 Fabiana Ursitti,1 Gabriele Monte,1 Giorgia Sforza,1 Massimiliano Valeriani,1-3 | 1Developmental Neurology Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy; 2Systems Medicine Department, Tor Vergata University of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark
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PO-87 | Dual inhibition of FAAH and TRPV1 receptors counteracts nitroglycerin-induced migraine-like symptoms only in male rats Miriam Francavilla,1,2 Sara Facchetti,1,2 Chiara Demartini,1 Anna Maria Zanaboni,1,2 Michela Palmisani,3 Valentina Franco,3 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia; 2Department of Brain and Behavioral Sciences, University of Pavia; 3Department of Internal Medicine and Therapeutics, Clinical and Experimental Pharmacology Unit, University of Pavia, Italy
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PO-53 | Managing chronic primaryhHeadache in Lombardy: insights from the ‘PERLA’ project Grazia Sances,1 Claudia Sulmona,1 Natascia Ghiotto,1 Daniele Martinelli,1 Licia Grazzi,2 Alberto Raggi,2 Danilo Antonio Montisano,2 Matilde Leonardi,2 Giulia Gandini,2 Renata Rao,3 Alessandro Padovani,3 Alessandro Amorosi,5 Cristina Tassorelli,1,5 on behalf of Rete Regionale Cefalee Lombardia | 1Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation Pavia, Italy; 2Headache Center, IRCCS Fondazione Istituto Neurologico Carlo Besta, Milan, Italy; 3ASST Spedali Civili di Brescia, Italy; 4Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; 5Struttura Reti Clinico-Assistenziali e Organizzative e Ricerca, U.O. Polo Ospedaliero Direzione Generale Welfare, Regione Lombardia, Italy
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PO-21 | Evaluating the impact of anti-CGRP monoclonal antibodies on retinal features in migraine patients: a retrospective optical coherence tomography study Chiara Serafini,1 Massimo Cesareo,2 Alessio Martucci,2 Marco Lombardo,2 Vittoria Carla D’Agostino,1 Alessandro Stefani,3 Carlo Nucci,2 Nicola Biagio Mercuri,1,3 Maria Albanese1,3 | 1Regional Referral Headache Center, Neurology Unit, Tor Vergata University Hospital, Rome, Italy 2Ophthalmology Unit, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome; 3Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, Italy
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OC-13 | Monoclonal antibodies targeting CGRP differently affect sleep and psychiatric comorbidities in reproductive and postmenopausal chronic migraine women Giulia Procopio, Letizia Curto, Antonia Di Chirico, Leonardo Troilo, Gabriele Siciliano, Filippo Baldacci, Sara Gori | Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa-AOUP, Pisa, Italy
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PO-73 | Auricular acupuncture as a complementary treatment for tension-type headache in women: a prospective study on efficacy and safety Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-40 | Evaluating agreement between physician and ChatGPT in migraine prophylaxis selection: a pilot comparative study Simone Vigneri1, MatteoZanella2, Gianfranco Sindaco2, Alberto Merlin2, Maria Mazzullo2, Marco La Grua2, Valentina Paci2, Carmen Bertone2, Gilberto Pari2 1Santa Maria Maddalena Hospital, Neurology, Occhiobello, Italy; 2Santa Maria Maddalena Hospital, Pain Medicine, Occhiobello, Italy
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PO-08 | Long-term outcome in pediatric patients with headache S. Genta,1,2 M. Celario1,2, C. Brancaccio¹ ², G. Rossetto,1,2 C. Dusi,1,2 P. Baso,1,2 V. De Giorgis1,2 | 1Department of Child Neuropsychiatry, IRCCS Mondino, Pavia; 2University of Pavia, Italy
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PO-59 | Questioning online survey-based physiotherapy treatment referral in headache treatment: differences in developed and developing countries D. Onan,1,2 A.K. Erdemoğlu,3 P. Gelener,4 S. Velioğlu,5 S. Ulutaş,6 N. Taşdemir,7 M. Waliszewska-Prosół,8 E. Ekizoğlu,9 M. Straburzyński,10 M. Kodounis,11 B. Raffaelli,12 C. Tana,13 F. De Cesaris,14 R. Messina,15 E.I. Sen,16 S. Ray,17 G. Sebastianelli,18 F. Granella,19 U. Pensato,20 S. Crema,21 S. Cevol,22 K. Chakravarty,23 M. Pia Prudenzano,24 A. Casalena,25 M. Romozzi,26 T. Takizawa,26 W. Rattanawong,27 A. Gantenbein,28 V. Favoni,29 C. Gaul,30 L.F.I. Iannone,31 B. Schäfer,23 D.A. Montisano,33 O. Grosu,34 A.B. de Oliveira,35 F. Puledda,36 V. Romanenko,37 I. Ros González,38 M. Castaldo,39 H. Al-Khazali,40 A. Hassan,41 D. Garcia-Azorin,42 L.-L. Hope Pan,43 R. Gil-Gouveia,44 M. Sanchez del Rio,45 M. Lisicki,46 H.W. Schytz,47 P. Anukoolwittaya,48 T. Mavridis,49 M. Lanteri-Minet,50 D.B. Swerts,51 C. Altamura,52 K. Hirata,53 M. Togha,54 M. Kyung Chu,55 T. Pongpitakmetha,56 M.-H. Bjørk,57 M. Minen,58 K. Skorobogatykh,59 D. Chowdhury,60 A.-M. Torgersen Dalgeir,61 J. Versijpt,62 P. Cras,63 A. Govaerts,64 A. Chiarugi,65 N. Vashchenko,59 L. Dobbels,66 T.S. Monteith,67 F. De Bruyne,68 E. Garay,67 S.L. Sava,69 Z. Salinas,67 M. Nordtveit,70 K. Delmotte,71 A. Gonzalez-Martinez,72 S. Debray,73 C. Deligianni,74 W. De Hertogh,75 R. Castien,76 E. Caronna,77 C. Valerija,78 F. Ahmed,79 G. De la Meilleure,80 L.L. Panneerchelvam,81 G.H. Bringeland,82 R. Ornello,2 S. Sacco2 | 1Yozgat Bozok University, Physiotherapy and Rehabilitation, Ankara, Turkey;2University of L'Aquila, Department of Biotechnological and Applied Clinical Sciences, L'Aquila, Italy;3Clinic of Prof. Dr. Ali Kemal Erdemoğlu, Neurology, Ankara, Turkey;4Elite Research and Surgical Hospital , Nicosia, Cyprus;5Karadeniz Technical University, Department of Neurology, Trabzon, Turkey;6Bahcesehir University, Department of Neurology, İstanbul, Turkey;7Ağrı İbrahim Çeçen University, Department of Neurology, Ağrı, Turkey;8Wroclaw Medical University, Wroclaw, Germany;9Istanbul University, Department of Neurology, Istanbul, Turkey;10University of Warmia and Mazury, Olsztyn, Poland;11National & Kapodistrian University of Athens, First Neurology Department, Eginitio Hospital, School of Medicine, Athens, Greece;12Charité Universitätsmedizin Berlin, Department of Neurology,Headache Center, Berlin, Germany;13SS Annunziata Hospital of Chieti, Chieti, Italy;14Centro Cefalee e Farmacologia Clinica - AOU Careggi , Florence, Italy;15Vita-Salute San Raffaele University, Milano, Italy;16Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation, İstanbul, Turkey;17Department of Neurology, PGIMER, Chandigarh, India;18Sapienza University of Rome, Latina, Italy;19University of Parma, Parma, Italy;20Humanitas University, Milan, Italy;21Fleni Hospital, Buenos Aires, Argentina;22University of Bologna, Bologna, Italy;23Post Graduate Institute Of Medical Education and Research, Chandigarh, India;24AOUC Policlinico, Centro Cefalee - Clinica Neurologica L Amaducci, Bari, Germany;25Centro Cefalee UOC Neurologia, Teramo, Italy;26Keio University School of Medicine, Tokyo, Japan;27King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand;28ZURZACH Care, Zürich, Switzerland;30IRCCS Istituto delle scienze neurologiche di Bologna, Bologna, Italy;30Headache Center Frankfurt, Frankfurt, Germany;31Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy, Modena, Italy;32Migraine and Headache Clinic Königstein , Frankfurt, Germany;33SSD Centro Cefalee - Fondazione IRCCS Istituto Neurologico C.Besta, Milan, Italy;34Diomid Gherman Institute of Neurology and Neurosurgery, Kişinev, Moldova;35Center for Clinical and Epidemiological Research, University of Sao Paulo , Sao Paolo, Brazil;36King's College London, London, United Kingdom;37Vita Medical Clinic, Kyiv, Ukraine;38Hospital Clínico Universitario de Valladolid, Vallodolid, Spain;39Parma University, Parma, Italy;40Danish Headache Center, Copenhagen, Denmark;41Cairo University , Cairo, Egypt;42University of Valladolid, Valladolid, Spain;43Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan;44Hospital da Luz. Lisboa, Lisboa, Portugal;45Clinica Universidad de Navarra, Navarra, Spain;46Mercedes & Martín Ferreyra Institute for Medical Research, Córdoba, Argentina;47University of Copenhagen, Copenhagen, Denmark;48King Chulalongkorn Memorial Hospital, Bangkok, Thailand;49Tallaght University Hospital, Dublin, Ireland;50CHU Nice and Cote D'azur University, Nice, France;51Santa Casa de Sao Paolo, Sao Paolo, Brazil;52Fondazione Policlinico Universitario Campus BIo-Medico, Rome, Italy;53Dokkyo Medical University, Mibu, Tochigi, Japan;54Tehran University, Tehran, Iran;55Yonsei University, Seoul, South Korea;56Chulalongkorn University, Bangkok, Thailand;57University of Bergen , Bergen, Norway;58NYU Langone Health, New York, United States;59University Headache Clinic, Moscow, Russian Federation;60 G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India;61Haukeland University Hospital, NorHead, Bergen, Norway;62UZ Brussel, Brussel, Belgium;63Universiteit Antwerpen, Antwerpen, Belgium;64Rz Tienen, Tienen, Belgium;65University of Florence, Florence, Italy;Neurology Department İmelda Ziekenhuis, Bonheiden, Belgium;67University of Miami, Miami, United States;68University College Ghent, Ghent, Belgium;69University of Liège, Liege, Belgium;70Haukeland Universitetssykehus, Bergen, Norway;71Universitair Ziekenhuis Leuven, Leuven, Belgium;72Hospital Universitario de la Princesa e Instituto de Investigación Sanitaria Princesa, Madrid, Spain;73Europa Ziekenhuizen, Brussel, Belgium;74Athens Naval Hospital, Athens, Greece;75University of Antwerp , Antwerpen, Belgium;76Vrije Universiteit Amsterdam, Amsterdam, Netherlands;77Vall d'Hebron Hospital, Barcelona, Spain;78Private hospital, Riga, Latvia;79Hull University, Hull, United Kingdom;80VITAZ - General Hospital, Sint-Niklaas, Belgium;81James Cook University Hospital, Middlesbrough, United Kingdom; 82Haukeland University Hospital, Bergen, Norway
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PO-27 | A monitoring of intracranial hypertension through the valuation of optic nerve sheath diameter with bedside ultrasounds. A case report Antonio Taglialatela,1 Camilla Gaiga,1 Simone Lorenzut,2 Enrico Belgrado,2 Mariarosaria Valente1,3 | 1Clinical Neurology Unit, Department of Head, neck and neurosurgery, Udine University Hospital, Udine; 2Neurology Unit, "Head, Neck and Neurosciences" Department, University Hospital of Udine; 3Department of Medical Area, University of Udine, Udine, Italy
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OC-19 | A multicenter, retrospective case series of trigeminal autonomic cephalalgias in children and adolescents Alessandro Borrelli,1 Vittorio Sciruicchio,2 Alessandro Ferretti,3 Irene Toldo,4 Antonia Versace,5 Elisabetta Tozzi,6 Agnese Onofri,7 Giorgia Sforza,1 Gabriele Monte,1 Fabiana Ursitti,1 Massimiliano Valeriani,1,8,9 Laura Papetti1 | 1Developmental Neurology Unit, IRCCS Bambino Gesù Children's Hospital, Rome; 2Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari;3Department of Neuroscience, Mental Health & Sense Organs (NESMOS), Faculty of Medicine & Psychology, Sant'Andrea Hospital, Rome; 4Pediatric Neurology and Neurophysiology Unit, Department of Woman's and Child Health, University of Padua; 5A.O.U. Città della Salute e della Scienza di Torino, Department of Pediatric Emergency, Regina Margherita Children's Hospital, Turin; 6Department of Clinical Medicine, Public Health, Life and Environmental Sciences, L'Aquila; 7Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; 8Tor Vergata University of Rome, Systems Medicine Department, Rome, Italy; 9Aalborg University, Center for Sensory-Motor Interaction, Aalborg, Denmark
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PO-79 | Survey on adherence and tolerability of atogepant used as migraine preventive treatment D.A. Montisano,1 G. Vaghi,2,3 A. Paris,1 R. De Icco,2,3 B. Agostini,2,3 M. Giraudo,2,3 A. Solfrizzi,2,3 C. Tassorelli,2,3 G. Sances,3 L. Grazzi | 1Fondazione IRCCS C.Besta Istituto Neurologico, SSD Headache Center, Milan, Italy; 2University of Pavia, Department of Brain and Behavioral Sciences, Pavia, Italy; 3IRCCS Mondino Foundation, Headache Science & Neurorehabilitation Unit, Pavia, Italy
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PO-46 | Diagnostic tests and headache misdiagnoses in individuals with resistant and refractory migraine – data from the REFINE study Federico De Santis,1 Chiara Rosignoli,1 Agnese Onofri,1 Mark Braschinsky,2 Olga Sved,2 Raquel Gil-Gouveia,3,4 Renato Oliveira,3 Christian Lampl,5 Jakob Paungarttner,5 Paolo Martelletti,6 William David Wells-Gatnik,7 Isabel Pavao Martins,8 Dimos D Mitsikostas,9 Loukia Apostolakopoulou,9 Aynur Ozge,10 Dilan Bayar Narin,10 Patricia Pozo-Rosich,11 Albert Munoz-Vendrell,11 Maria Pia Prudenzano,12 Martino Gentile,12 Kristina Ryliskiene,13 Jurgita Vainauskiene,14 Margarita Sanchez-del-Rio,15 Fabrizio Vernieri,16 Gianmarco Iaccarino,16 Marta Waliszewska-Prosół,17 Sławomir Budrewicz,17 Marta Carnovali,18 Zaza Katsarava,18 Simona Sacco,1 Raffaele Ornello1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy; 2Department of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu and Neurology Clinic of Tartu University Hospital, Tartu, Estonia; 3Headache Center, Neurology Department, Hospital da Luz, Lisboa, Portugal; 4Center for Interdisciplinary Research in Health, Universidade Católica Portuguesa, Lisboa; 5Headache Medical Center, Seilerstaette Linz, Linz, Austria; 6Unitelma Sapienza University of Rome, Italy; 7Texas Tech University Health Sciences Center, El Paso TX, USA; 8Centro de Estudos Egas Moniz, Faculty of Medicine, University of Lisbon, Lisbon, Portugal; 9First Department of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece; 10Department of Neurology, Mersin University Medical Faculty, Mersin, Turkey and NOROM Neuroscience and Neurotechnology Center of Excellence, Ankara, Turkey; 11Headache Unit, Neurology Department, Vall d’Hebron University Hospital, Headache and Neurological Pain Research Group, VHIR, Barcelona, Spain; 12Headache Center, “I. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy; 13Center of Neurology, Vilnius University, Vilnius, Lithuania; 14Center of Neurology, Kardiolitos klinikos, Vilnius, Lithuania; 15Department of Neurology, Clínica Universidad de Navarra, Madrid, Spain; 16Unit of Headache and Neurosonology, Fondazione Policlinico Campus Bio-Medico and Neurology, Università Campus Bio-Medico di Roma, Roma, Italy; 17Department of Neurology, Wroclaw Medical University, Wrocław, Poland; 18Department of Neurology, Christian Hospital Unna and University of Duisburg-Essen, Ruhr Metropolitan, Germany
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PO-14 | Pain catastrophizing in chronic migraine patients receiving eptinezumab treatment Alessandra Parisi,1 Licia Grazzi,1 Alberto Raggi,2 Giulia Regonesi,1 Montisano Danilo Antonio1 | 1Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano; 2Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy
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OC-06 | Migraine in the elderly: a retrospective study in a tertiary headache center Giulia Paparella,1,2 Stefania Scannicchio,1 Annalisa Di Dio,1 Emmanuella Ladisa,1 Chiara Abbatantuono,1 Elena Ammendola,1 Katia Ricci,1 Giusy Tancredi,1 Livio Clemente,1 Marianna Diletta Delussi,3 Marina de Tommaso1 | 1Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Bari; 2IRCCS Neuromed, Pozzilli (IS; 3Department of Education, Psychology, Communication (For.Psi.Com.), University of Bari Aldo Moro, Bari, Italy
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PO-66 | Predicting the evolution to resistant and refractory migraine: a machine learning analysis from the REFINE Study Chiara Rosignoli,1 Raffaele Ornello,1 Daniele Lozzi,2 Enrico Mattei,2 Federico De Santis,1 Agnese Onofri,1 Mark Braschinsky,3 Christian Lampl,4 Isabel Pavão Martins,5 Paolo Martelletti,6 Dimos Mitsikostas,7 Raquel Gil-Gouveia,8 Maria Pia Prudenzano,9 Kristina Ryliskiene,10 Margarita Sanchez del Rio,11 Patricia Pozo-Rosich,12 Aynur Özge,13 Fabrizio Vernieri,14 Marta Waliszewska-Prosół,15 Zaza Katsarava,16 Giuseppe Placidi,2 Simona Sacco1 | 1Dept. of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; 2A²VI-lab, Dept. MeSVA University of L’Aquila; 3Dept. of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Estonia; 4Headache Medical Center, Seilerstaette Linz, Austria. Center; 5Headache Center, Hospital da Luz, Lisbon, Portugal; 6School of Health, Unitelma Sapienza University of Rome, Italy; 7First Dept of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Greece; 8Centro de Estudos Egas Moniz, Faculty of Medicine, University of Lisbon, Portugal; 9Headache Center, Amaducci Neurological Clinic, Policlinico General Hospital, Bari, Italy; 10Center of Neurology, Vilnius University, Lithuania; 11Dept. of Neurology, Clínica Universidad de Navarra, Madrid, Spain; 12Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain; 13Dept. of Neurology, Mersin University Medical Faculty, Mersin, Turkey; 14Università Policlinico Campus Bio-Medico, Rome, Italy; 15Dept. of Neurology, Wroclaw Medical University, Wrocław, Poland; 16Dept of Neurology, Christian Hospital Unna and University of Duisburg-Essen, Ruhr Metropolitan, Germany
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PO-33 | Visual hallucinations: a non-unique symptom Francesca Traccitto, Giada Giuliani, Davide Chiffi, Chiara Zilli, Mariangela Fratino, Marta Altieri | Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy
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PO-01 | Pediatric nummular headaches: a case series and physiopathological and nosography considerations Carola Meo¹*, Sofia D’Agostino¹*, Antonella Morea²*, Martina Tarantini²*, Giuseppe Giglia³, Maria Rosita Ruta⁴, Edvige Correnti⁵, Daniela D’Agnano², Giuseppe Santangelo⁵, Vittorio Sciruicchio², Vincenzo Raieli⁵ (*These authors contributed equally) | 1Child Neuropsychiatry Unit Department, Pro.M.I.S.E. "G. D'Alessandro", University of Palermo, Palermo, Italy; 2Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari, Bari, Italy; 3Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Section of Human Physiology, University of Palermo, Palermo; 4Child Neuropsychiatry Unit, ASP 6, Palermo; 5Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo, Italy
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PO-85 | Alterations in gut microbiota and the endocannabinoid system in an animal model of chronic migraine Sara Facchetti,1,2 Chiara Demartini,1 Miriam Francavilla,1,2 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; 2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy
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PO-52 | Long-term efficacy of CGRP mAbs: new insights and current evidence Oreste Marsico,1 Marta Lioi,2 Rosario Iannacchero,3 Michele Trimboli3 | 1Department of Neuroscience, “Giovanni Paolo II” Hospital, Lamezia Terme, Catanzaro, Italy; 2Department of Neurology, Magna Graecia University, Catanzaro, Italy; 3Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-20 | Phenotypic description of a multigenerational family with PRRT2 gene mutation: a case series of six members affected by hemiplegic migraine and paroxysmal events Fabiana Cerulli,1 Costanza Sottani,1 Giulia Di Lazzaro,1,2 Paolo Calabresi,1,2 Anna Rita Bentivoglio,1,2 Catello Vollono1,3 | 1Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Rome; 2UOC Neurologia, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy; 3Neurofisiopatologia, Dipartimento di Scienze dell'invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy
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OC-12 | The potential role of sleep quality in the relationship between glymphatic function and migraine frequency: insights from a cross-sectional study Maria Grazia Vittorini, Raffaele Ornello, Federico Salfi, Antonio Innocenzi, Federico De Santis, Federico Bruno, Francesca Pistoia, Michele Ferrara, Alessandra Splendiani, Simona Sacco | Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy
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PO-72 | Stigma in migraine: preliminary results from the “Studio Emicrania Maugeri” Project Luca Giani, Christian Lunetta | Istituti Clinici Scientifici Maugeri IRCCS, Neurological Rehabilitation Unit of Milano Institute, Milan, Italy
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PO-39 | Leeds Dependence Questionnaire (LDQ) in migraine: diagnostic utility without predictive value for anti-CGRP (R) response Antonio Munafò,1 Andrea Burgalassi,1 Giulia Vigani,2 Francesco De Cesaris,1 Alberto Chiarugi1,2 | 1Headache Center and Clinical Pharmacology Unit, Careggi University Hospital, Florence, Italy; 2Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy
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PO-07 | Psychological management of children treated at the Pediatric Headache Centre of Turin: preliminary analysis Emanuela Serri, Annachiara Lamberti Zanardi, Raffaella Mascolo, Barbara Lauria, Roberta Rossi, Sara Simona Racalbuto, Antonia Versace, Claudia Bondone | Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin, Italy
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