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PO-11 | Resting state high-density EEG analysis reveals interictal subcortico-cortical linear and non-linear anomalies in subjects with migraine Gabriele Sebastianelli,1 Camillo Porcaro,2 Sara Gilli,1 Chiara Abagnale,1 Francesco Casillo,2 Giorgio Di Lorenzo,3 Gianluca Coppola1 | 1Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino ICOT, Latina; 2Department of Neuroscience (DNS) and Padova Neuroscience Center (PNC), University of Padova; 3Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Italy
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OC-03 | Transcranial magnetic stimulation in patients with chronic migraine and medication overuse headache Elisa Maria Piella,1 Fabio Ferrandes,1 Gianluca Isoardo,1 Alberto Mario Chiarandon,1 Fausto Roveta,1 Alessia Agostinelli,1 Elisa Rubino,1,2 Innocenzo Rainero,1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin; 2Headache Center, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Turin, Italy
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PO-63 | Acceptance and commitment therapy in the management of chronic headache pain E. Principe,1 M. Pirrotta,1 N. Fava,2 C. Marchio,1 L. M. Catalano,1 D. Bosco,2 R. Iannacchero,2 Alcmeone group | 1SPDC ASP Catanzaro, 2Centro Cefalee AOU R. Dulbecco Catanzaro, Italy
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PO-30 | A chronic migraine phenotype unveiling acromegaly: diagnostic pitfalls and the impact of timely treatment Cinzia Rita Tamborino, Gianni Difonzo, Adriana Fallacara, Damiano Paolicelli, Maria Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy
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OC-22 | Beyond headache: prevalence of atopy and other comorbidities in pediatric patients Erica Agosto,1 Alessandra Fera,1 Giulia Grasso,2 Barbara Lauria,2 Roberta Rossi,2 Cristina Vassia,2 Emanuele Castagno,2 Antonia Versace2 | 1Department of Public Health and Pediatrics, Postgraduate School of Pediatrics, University of Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin, Italy
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PO-82 | Integrated approach with detoxification, CGRP monoclonal antibodies and psychoeducational support in two patients with complex medication overuse headache Claudia Lanni,1 Federica Papini,2 Chiara Prevost,3 Alessandro Canessa,3 Lucia Testa,3 Cristoforo Comi,2 Delfina Ferrandi3 | 1Department of Psychology “Santi Antonio e Biagio”, University Hospital, Alessandria, Italy; 2Neurology Unit, Department of Transitional Medicine, University of Piemonte Orientale, and University Hospital “Maggiore della Carità”, Novara, Italy; 3Neurology Unit, “Santi Antonio e Biagio” University Hospital, Alessandria, Italy
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PO-49 | Distress perception and mutuality in caregivers of migraine patients with depressive symptoms.: baseline evaluation of the observational prospective real-life MiDEAR study to evaluate the effectiveness of fremanezumab for reducing the caregivers’ burden a C. Altamura,1 L. Fofi,1 R. Ornello,2 G. Ceccardi,3 C. Aurilia,4 A. Montisano,5 I. Orologio,6 D. Mascarella,7 G. Viticchi,8 M. Marcosano,1 N. Brunelli,1 G. Del Mastro,1 A. Onofri,2 A. Lanfranchi,3 G. Fiorentini,4 M. Silvestro,6 V. Favoni,7 G. Egeo,4 M. Silvestrini,8 M. Peresson,9 S. Cevoli,7 A. Russo,6 R. Rao,3 L. Grazzi,5 S. Sacco,2 F. Vernieri1 | 1Fondazione Policlinico Universitario Campus Bio-Medico, Rome; 2University of L'Aquila, L’Aquila; 3ASST Spedali Civili di Brescia, Brescia; 4IRCCS San Raffaele, Rome; 5IRCCS Fondazione istituto Neurologico Carlo Besta, Milan; 7IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna; 6University of Campania; Caserta; 8Marche Polytechnic University, Ancona; 9San Pietro Fatebenefratelli Hospital, Rome, Italy
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PO-17 | A clinical guide to assess and manage altered pain sensitivity and cervical musculoskeletal impairments migraine patients. Part 1: Assessment and profiling Stefano Di Antonio,1,2 Lars Arendt-Nielsen,1 Matteo Castaldo1,3 | 1Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), SMI, School of Medicine, Aalborg University, Aalborg, Denmark; 2Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa; 3Department of Medicine and Surgery, Clinical Psychology, University of Parma, Italy
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OC-09 | Atogepant in treatment-refractory chronic migraine: is a revision of current criteria for refractory migraine appropriate? Lorenzo Tartaglione, Marcello Silvestro, Ilaria Orologio, Marcella Marziani, Francesco Maurizio Chianese, Pasquale Sozio, Alessandro Tessitore, Gioacchino Tedeschi, Antonio Russo | Headache Center, Department of Advanced Medical and Surgical Sciences (DAMSS), University of Campania "Luigi Vanvitelli", Naples, Italy
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PO-69 | Three-month atogepant treatment modulates dopaminergic-related functional connectivity in episodic migraine Davide Fedeli,1 Danilo Antonio Montisano,1 Greta Demichelis,1 Giuseppe Ciullo,1,2 Jean Paul Medina Carrion,1 Maria Grazia Bruzzone,1 Emilio Ciusani,1 Alessandra Erbetta,1 Marina Grisoli,1 Erika Guastafierro,1 Domenico D’Amico,1 Alberto Raggi,1 Anna Nigri,1 Licia Grazzi1 | 1Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; 2University of Parma, Parma, Italy
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PO-36 | An atypical presentation of Tolosa-Hunt Syndrome: a case report Marco Bolchini, Matteo Cortinovis, Paola Zavarise, Giulia Campana, Giorgio Dalla Volta | Neurology Unit and Headache Center, Istituto Clinico Città di Brescia, Brescia, Italy
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PO-04 | Mindfulness-based behavioral intervention for adolescents with high-frequency primary headaches: feasibility of a prospective multicenter study Beatrice Baldo,1 Giulia De Lorenzi,1 Valeria Marletta,1 Ilaria Bonemazzi,1 Alessia Raffagnato,2 Cristina Vassia,3 Emanuela Serri,3 Antonella Versace,4 Daniela D’Agnano,4 Vittorio Sciruicchio,4 Licia Grazzi,5 Irene Toldo1 | 1Juvenile Headache Center, Department of Woman’s and Child’s Health, University of Padua; 2Child and Adolescent Neuropsychiatric Unit, Department of Women's and Children's Health, University of Padua; 3Pediatric Headache Center, Department of Pediatric Emergency, Regina Margherita Children's Hospital, Turin; 4Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari; 5Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
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PO-89 | Alcohol and headache: an update Alessandro Panconesi,1,2 Maria Letizia Bartolozzi1 | 1Headache Centre, Department of Neurology, Health Authority, Empoli; 2Clinical Research Institute Ecomedica, Empoli, Italy
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PO-55 | What patients want: a qualitative study on an information resource on migraine Matteo Castaldo,1 Zhiqi Liang,2 Gina Williams,2 Shayne Watson,2 Caitlyn Haynes,2 Zoe Diamond2 | 1Parma University; 2University of Queensland
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PO-23 | Hemicrania continua-like headache in familial SDHD-related paragangliomas: a diagnostic challenge A. Di Chirico, L. Curto, G. Procopio, L. Troilo, G. Siciliano, F. Baldacci, S. Gori | Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa-AOUP, Pisa, Italy
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OC-15 | Electroencephalography recording during visual aura in migraine: results by quantitative analysis Salvatore Maria Lima,1 Massimo Gangitano,1 Vincenzo Di Stefano,1 Vincenzo Raieli,2 Filippo Brighina1 | 1Department of Biomedicine, Neuroscience, and advanced Diagnostic (BIND), University of Palermo; 2Child Neurology and Psychiatry Unit-ISMEP, "G. Di Cristina" Children's Hospital-ARNAS Civico, Palermo, Italy
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PO-75 | Network meta-analysis comparing efficacy and safety outcomes of atogepant, rimegepant, and galcanezumab in patients with episodic migraine after including CHALLENGE-MIG Trial Jessica Ailani,1 Pranav Gandhi,2 Anjana Lalla,2 Peter McAllister,3 Tanya Bilchik,4 Stephanie Nahas,5 David Rowe,6 Cristiano Piron,6 Kari Kelton,6 Raffaello Masselli*, Rashmi Halker Singh7 | 1MedStar Health, Washington DC, USA; 2AbbVie, North Chicago, IL, USA; 3New England Institute for Neurology and Headache, Stamford, CT USA; 4Department of Neurology, Yale School of Medicine, New Haven, CT, USA; 5Department of Neurology, Thomas Jefferson University, Philadelphia, PA USA; 6Medical Decision Modeling Inc., Indianapolis, IN, USA; 7Mayo Clinic, Phoenix, AZ, USA *Abbvie Srl, Rome, Italy. This individual has been added to this publication author by-line, with the permission of the original authors, for the express purpose of conducting the presentation at a local congress or in a local language. He did not contribute to the content of the publication.
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PO-42 | OnaBotulinumtoxin-A in chronic migraine patients with short or long disease history and psychiatric comorbidities: preliminary data from an Italian multicentric study (the BACH Study) Fabrizio Vernieri,1,2 Marilena Marcosano,2 Licia Grazzi,3 Danilo Antonio Montisano,3 Raffaele Ornello,4 Simona Sacco,4 Chiara Rosignoli,4 Alberto Doretti,5 Maria Albanese,6 Giovanna Viticchi,7 Nicoletta Brunelli, Luigi d’Onofrio,2 Luisa Fofi,1 Claudia Altamura,1,2 Patrizio Pasqualetti8 | 1Fondazione Policlinico Campus Bio-Medico, Roma, Italy; 2Università Campus Bio-Medico di Roma, Italy; 3Istituto Neurologico Besta, Milano, Italy; 4Università degli Studi l’Aquila, Italy; 5Istituto Auxologico, Milano, Italy; 6Policlinico Tor Vergata, Roma, Italy; 7Università Politecnica Marche, Italy; 8Sapienza Università di Roma, Italy
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PO-10 | Differential diagnosis between symptomatic focal occipital epilepsy and headache: a case report Federica Molaschi,1 Barbara Lauria,2 Giulia Grasso,2 Cristina Vassia,2 Francesca Torta,3 Antonia Versace,2 Carlotta Canavese3 | 1University of Turin, SC U Child Neuropsychiatry, Regina Margherita Hospital, Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin; 3Department of Child Pathology and Care “Regina Margherita”, SSD Pediatric Neurology, Regina Margherita Children’s Hospital, Turin, Italy
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OC-02 | Role of specific microRNAs in cluster headache: association with disease phenotype and neuropeptide levels A. Solfrizzi,1,2 F. Cammarota,1,2 R. De Icco,1,2 F. Bighiani,1,2 M. Corrado,2 G. Vaghi,1,2 A. Antoniazzi,1,2 V. Grillo,1,2 M. Giraudo,1,2 B. Agostini,1,2 R. Greco,2 C. Demartini,1,2 M. Francavilla,1,2 S. Franchini,1,2 M. Allena,2 G. Sances,2 C. Tassorelli1 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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PO-62 | Preventive migraine treatment in patients under 25: a 24-month observational study on adherence, therapeutic switching, and prescription determinant factors Marilena Marcosano,1 Nicoletta Brunelli,1 Luisa Fofi,1 Laura Papetti,2 Fabiana Ursitti,2 Massimiliano Valeriani,2 Fabrizio Vernieri,1 Claudia Altamura1 | 1Headache and Neurosonology Unit, Fondazione Policlinico Campus Biomedico di Rome, Rome, Italy; 2Developmental Neurology, Bambino Gesù Children Hospital, IRCCS, Rome, Italy
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PO-29 | Spontaneous intracranial hypotension: a clinical and radiological observational study F. Verna, D. Mascarella, V. Favoni, G. Pierangeli, L. Cirillo, S. Cevoli | IRCCS Istituto delle Scienze Neurologiche di Bologna, Italia DIBINEM, Alma Mater Studiorum Bologna, Italy
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OC-21 | Coping and pain catastrophizing in migraine patients and their mothers: a comparison between mothers with and without migraine Martina Proietti Checchi,1 Samuela Tarantino,1 Fabiana Ursitti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Massimiliano Valeriani,1,2,3 Laura Papetti1 | 1Developmental Neurology, Bambino Gesù Children Hospital, IRCCS, Rome, Italy; 2Child Neurology and Psychiatry Unit, Tor Vergata University of Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark
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PO-81 | Knowledge and misconceptions on headache disorders among healthcare workers: preliminary results from the Studio Emicrania Maugeri Study Luca Giani, Christian Lunetta | Istituti Clinici Scientifici Maugeri IRCCS, Neurological Rehabilitation Unit of Milano Institute, Milan, Italy
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PO-48 | Flunarizine for preventive treatment of hemiplegic migraine during pregnancy: a case report Andrea Burgalassi,1 Antonio Munafò,2 Francesco De Cesaris,1 Giulia Vigani,2 Alberto Chiarugi1,2 | 1Headache Center and Clinical Pharmacology Unit, Careggi University Hospital, Florence, Italy; 2Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy
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PO-16 | Neurophysiological effects of atogepant in high-frequency episodic migraine B. Agostini,1,2 F. Cammarota,1,2 R. De Icco,1,2 V. Grillo,1,2 G. Vaghi,1,2 F. Bighiani1,2, M. Corrado,2 A. Antoniazzi,1,2 M. Giraudo,1,2 A. Solfrizzi,1,2 R. Greco,2 C. Demartini,1,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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OC-08 | Daily eletriptan significantly improves treatment-resistant cluster headache: a case series Andrea Burgalassi,1 Antonio Munafò,2 Francesco De Cesaris,1 Giulia Vigani,2 Alberto Chiarugi1,2 | 1Headache Center and Clinical Pharmacology Unit, Careggi University Hospital, Florence; 2Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy
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PO-68 | Bipolar disorder spectrum and psychopathology in cluster headache compared to migraine: a cross-sectional study in a hospital headache clinic Isabella Getuli, Giada Giuliani, Chiara Zilli, Simone Preti, Gaia Chiecchi, Lorenzo Tarsitani, Marta Altieri | Dipartimento di Neuroscienze Umane, Sapienza Università di Roma, Italy
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PO-35 | Treatment of chronic and episodic migraine with atogepant improves quality of life in patients with comorbid multiple sclerosis: the experience of the Headache Center at Spaziani Hospital, Frosinone Laura Borrello; Fabiana Marinelli; Maria Lorena Marziale; Ilaria Avallone; Fulvio Ferrante; Roberto De Simone | Neurology Unit, Headache Center, Multiple Sclerosis Center, UOC Pharmacy, Spaziani Hospital, Frosinone (FR), Italy
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PO-03 | Intracranial incidental findings on brain magnetic resonance imaging (MRI) in a pediatric population with primary headache: our experience and management Fabiana Ursitti,1 Filippo Tripodi,1 Laura Papetti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Samuela Tarantino,1 Martina Proietti Checchi,1 Massimiliano Valeriani1-3 | 1Developmental Neurology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy; 2Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Department of Health Science and Technology, School of Medicine, Aalborg University, Aalborg, Denmark
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PO-88 | Can tamoxifen and metformin nullify efficacy of CGRP-mAbs migraine prophylaxis? Patrizia Rossi,1,2 Valentina Cima,2 Alessandro Burlina2 | 1Headache Center, 2Neurology Department, San Bassiano Hospital, Bassano del Grappa (VI), Italy
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PO-54 | Patient perspectives on physiotherapy interventions for migraine: a pre- and post-intervention qualitative study Zhiqi Liang,1 Caitlin Scott,1 Felix Cabrera Manrique,1 Sumin Kim,1 Chun Shun Lee,1 Bixiang Cheng,1 Chun Yiu Kwok,1 Matteo Castaldo2 | 1University of Queensland; 2Parma University, Italy
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PO-22 | Impact of sleep disorders on anti-CGRP monoclonal antibodies treatment response in migraine: a cross-sectional study Costanza Sottani,1 Valerio Brunetti,1,2 Fabiana Cerulli,1 Claudia Garattini,4 Gianluca Avino,5 Paolo Calabresi,1,3 Catello Vollono1,4 | 1Università Cattolica del Sacro Cuore, Dipartimento di Neuroscienze, Rome; 2Stroke Unit, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 3UOC Neurologia, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 4UOC Neurofisiopatologia, Fondazione Policlinico Agostino Gemelli IRCSS, Rome; 5Unità di Neurologia, Ospedale Santo Stefano, Prato, Italy
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OC-14 | Efficacy of eptinezumab during a migraine attack: preliminary data from an Italian multicenter real-world experience (the BEFREE study) Luisa Fofi,1 Claudia Altamura,1 Marilena Marcosano,1 Alberto Doretti,2 Francesca Pistoia,3 Antonio Granato,4 Simona Guerzoni,5 Michele Trimboli,6 Licia Grazzi,7 Danilo Antonio Montisano,7 Gianluca Avino,8 Gabriele Sebastianelli,9 Carla Fasano,10 Elisa Maria Piella,11 Nicoletta Brunelli,1 Luigi Francesco Iannone,5,12 Fabrizio Vernieri1 on behalf of the Italian Headache Registry (RICe) Study Group | 1Neurosonology and Headache Unit, Fondazione Policlinico Campus Bio-Medico, Rome; 2IRCCS Istituto Auxologico Italiano - Department of Neurology and Laboratory of Neuroscience - Milan; 3University of L’Aquila; 4Headache Center, Neurology Clinic, University of Trieste, University Hospital of Trieste; 5AOU Policlinico di Modena; 6Azienda Ospedaliera-universitaria "Renato Dulbecco", Catanzaro; 7Headache Center, Neuroalgology Dpt, IRCCS Foundation "Carlo Besta" Neurological Institute, Milan; 8SOC Neurologia, Ospedale Santo Stefano, USL Toscana Centro, Prato; 9La Sapienza University of Rome Polo Pontino, Latina; 10Headache and Cerebrovascular Diseases Center, Neurology Unit 2, Careggi University Hospital, Florence; 11Department of Neuroscience “Rita Levi Montalcini”, University of Turin; 12Università di Modena e Reggio Emilia, Italy
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PO-74 | Effectiveness of auricular acupuncture in the management of menstrual migraine: a pilot study Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-41 | Eptinezumab for difficult-to-treat migraine: who responds and who needs more Alessandro Visentini,1,2,3 Roberta Messina,1,2,3 Ilaria Cetta,1,2,3 Edorardo Ratto,1 Laura Zanandrea,1,3 Federica Genovese,1,2,3 Irene Chinali,1 Bruno Colombo,1 Massimo Filippi1,2,3 | 1Neurology Unit and 2Neuroimaging Research Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3Vita-Salute San Raffaele University, Milan, Italy
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PO-09 | When migraine turns severe: a case of aura that lasts too long Alessandra Fera,1 Erica Agosto,1 Giulia Grasso,2 Cristina Vassia,2 Francesca Feyles,2 Carlotta Canavese,3 Sara Racalbuto,2 Antonia Versace2 | 1Department of Public Health and Pediatrics, University of Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin; 3Department of Child Pathology and Care “Regina Margherita”, SSD Pediatric Neurology, Regina Margherita Children’s Hospital, Turin, Italy
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OC-01 | Evolution of nitroglycerin-triggered premonitory symptoms in participants with migraine Gabriele Sebastianelli,1,2 Catarina Fernandes,1,3 Peter J. Goadsby,1 Nazia Karsan1 | 1NIHR King’s Clinical Research Facility, SLaM Biomedical Research Centre and Wolfson SPaRC, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, UK; 2Department of Medico-Surgical Sciences and Biotechnologies, Polo Pontino ICOT, Sapienza University of Rome, Latina, Italy; 3Neurology Department, Local Health Unit of Coimbra, Portugal
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PO-60 | Effectiveness of aerobic exercise, Mulligan technique, and myofascial release in migraine management: preliminary data from a randomized controlled trial Marco Bravi,1,2 Fabio Santacaterina,1,2 Federica Bressi,1,2 Francesca Nasto,1,2 Claudia Altamura,1,2 Fabrizio Vernieri1,2 | 1Fondazione Policlinico Universitario Campus Bio-Medico, Roma, Rome, Italy; 2Università Campus Bio-Medico di Roma, Rome, Italy
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PO-28 | Sex differences in the response to rimegepant for the treatment of acute migraine attacks – insights from the multicenter GAINER study Raffaele Ornello,1 Gloria Vaghi,2,3 Gabriele Sebastianelli,4 Francesco Casillo,4 Antonio Russo,5 Marcello Silvestro,5 Francesca Pistoia,1 Giorgio Dalla Volta,6 Matteo Cortinovis,6 Alberto Chiarugi,7 Danilo Antonio Montisano,8 Licia Grazzi,8 Maria Pia Prudenzano,9 Sabina Cevoli,10 Edoardo Mampreso,11 Gianluca Avino,12 Marina Romozzi,13 Mariarosaria Valente,14 Carla Fasano,15 Stefania Battistini,16 Antonio Granato,17 Elisa Maria Piella,18 Innocenzo Rainero,18 Federico De Santis,1 Simona Sacco,1 Maria Albanese,19 Michele Trimboli,20 Alberto Doretti,21 Cristina Tassorelli,2,3 Luigi Francesco Iannone,22 Roberto De Icco2,3 on behalf of the Italian Headache Registry (RICe) Study Group | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Brain and Behavioral Sciences, University of Pavia; 3Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 4Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina; 5Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples; 6Headache Center of Clinical Neurology of Istituto Clinico "Città di Brescia", Brescia; 7Department of Health Sciences, University of Florence; 8Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan; 9Headache Center, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari; 10IRCCS Istituto Di Scienze Neurologiche di Bologna, Programma Cefalee e Algie Facciali, Bologna; 11Headache Centre, Neurology - Euganea, Health Unit, Padua; 12Neurology Unit, Ospedale Santo Stefano, USL Toscana Centro, Prato; 13Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome; 14Clinical Neurology, Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero Santa Maria della Misericordia, Udine; 15Headache and Facial Pain Center Neurology, AOU Careggi, Florence; 16Department of Medical, Surgical and Neurological Sciences, University of Siena; 17Headache Centre, Clinical Unit of Neurology, School of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, ASUGI, University of Trieste; 18Department of Neurosciences “Rita Levi Montalcini”, University of Turin; 19Department of Systems Medicine, University of Rome Tor Vergata, Rome; 20University Magna Graecia, Catanzaro; 21Department of Neuroscience - Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan; 22University of Modena and Reggio Emilia, Modena, Italy
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OC-20 | The inflammatory burden index in pediatric migraine: a clinical study Carola Meo¹, Giulia Manfrè¹, Antonella Morea², Caterina Gaspari¹, Martina Tarantini², Maria Rosita Ruta³, Sofia D’Agostino¹, Edvige Correnti⁴, Daniela D’Agnano², Diletta Lopes⁴, Rosaria Nardello¹, Giuseppe Santangelo⁴, Vittorio Sciruicchio², Vincenzo Raieli⁴ | 1Child Neuropsychiatry Unit Department, Pro.M.I.S.E. "G. D'Alessandro", University of Palermo; 2Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari; 3Child Neuropsychiatry Unit, ASP 6 Palermo; 4Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo, Italy
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PO-80 | Real-world effectiveness of atogepant for the preventive treatment of migraine in a cohort of multi -refractory patients: a single center study M. De Luca,1 L. Ferraù,1 A. Cafarchio,2 M.S. Adragna,1 M. Autunno1 | 1Unit of Neurology and Neuromuscular Diseases, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy; 2Department of Medicine and Health Sciences “Vincenzo Tibero” DIMES, University of Molise, Campobasso, Italy
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PO-47 | Systemic ozone treatment in chronic migraine: a focus on disability reduction and medication use Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-15 | Disclosing somatosensory system alterations in trigeminal neuralgia Gianfranco De Stefano, Daniel Litewczuk, Enrico Evangelisti, Giuseppe Di Pietro, Pietro Falco, Eleonora Galosi, Caterina Leone, Francesca Caramia, Andrea Truini, Giulia Di Stefano | Department of Human Neuroscience, Sapienza University of Rome, Italy
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OC-07 | A retrospective analysis of headache and CADASIL association Danilo Antonio Montisano,1 Giulia Regonesi,1 Licia Grazzi,1 Alessandra Parisi,1 Alberto Raggi,2 Elisabetta Soldini,2 Giorgia Camarda,2 Matilde Leonardi,2 I. Canavero,3 E.M. Zacarias,3 Anna Bersano,3 Nicola Rifino3 | Fondazione IRCCS Istituto Neurologico Carlo Besta: 1SSD Centro Cefalee; 2SC Neurologia Salute Pubblica e Disabilità, 3SC Malattie Cerebrovascolari, Milan, Italy
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