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PO-62 | Preventive migraine treatment in patients under 25: a 24-month observational study on adherence, therapeutic switching, and prescription determinant factors Marilena Marcosano,1 Nicoletta Brunelli,1 Luisa Fofi,1 Laura Papetti,2 Fabiana Ursitti,2 Massimiliano Valeriani,2 Fabrizio Vernieri,1 Claudia Altamura1 | 1Headache and Neurosonology Unit, Fondazione Policlinico Campus Biomedico di Rome, Rome, Italy; 2Developmental Neurology, Bambino Gesù Children Hospital, IRCCS, Rome, Italy
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OC-21 | Coping and pain catastrophizing in migraine patients and their mothers: a comparison between mothers with and without migraine Martina Proietti Checchi,1 Samuela Tarantino,1 Fabiana Ursitti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Massimiliano Valeriani,1,2,3 Laura Papetti1 | 1Developmental Neurology, Bambino Gesù Children Hospital, IRCCS, Rome, Italy; 2Child Neurology and Psychiatry Unit, Tor Vergata University of Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark
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PO-81 | Knowledge and misconceptions on headache disorders among healthcare workers: preliminary results from the Studio Emicrania Maugeri Study Luca Giani, Christian Lunetta | Istituti Clinici Scientifici Maugeri IRCCS, Neurological Rehabilitation Unit of Milano Institute, Milan, Italy
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PO-48 | Flunarizine for preventive treatment of hemiplegic migraine during pregnancy: a case report Andrea Burgalassi,1 Antonio Munafò,2 Francesco De Cesaris,1 Giulia Vigani,2 Alberto Chiarugi1,2 | 1Headache Center and Clinical Pharmacology Unit, Careggi University Hospital, Florence, Italy; 2Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy
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PO-03 | Intracranial incidental findings on brain magnetic resonance imaging (MRI) in a pediatric population with primary headache: our experience and management Fabiana Ursitti,1 Filippo Tripodi,1 Laura Papetti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Samuela Tarantino,1 Martina Proietti Checchi,1 Massimiliano Valeriani1-3 | 1Developmental Neurology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy; 2Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Department of Health Science and Technology, School of Medicine, Aalborg University, Aalborg, Denmark
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PO-41 | Eptinezumab for difficult-to-treat migraine: who responds and who needs more Alessandro Visentini,1,2,3 Roberta Messina,1,2,3 Ilaria Cetta,1,2,3 Edorardo Ratto,1 Laura Zanandrea,1,3 Federica Genovese,1,2,3 Irene Chinali,1 Bruno Colombo,1 Massimo Filippi1,2,3 | 1Neurology Unit and 2Neuroimaging Research Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy; 3Vita-Salute San Raffaele University, Milan, Italy
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PO-80 | Real-world effectiveness of atogepant for the preventive treatment of migraine in a cohort of multi -refractory patients: a single center study M. De Luca,1 L. Ferraù,1 A. Cafarchio,2 M.S. Adragna,1 M. Autunno1 | 1Unit of Neurology and Neuromuscular Diseases, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy; 2Department of Medicine and Health Sciences “Vincenzo Tibero” DIMES, University of Molise, Campobasso, Italy
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PO-02 | Migraine in youth: a double challenge to cognition and emotion Samuela Tarantino,1 Martina Proietti Checchi,1 Laura Papetti,1 Fabiana Ursitti,1 Gabriele Monte,1 Giorgia Sforza,1 Massimiliano Valeriani,1-3 | 1Developmental Neurology Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy; 2Systems Medicine Department, Tor Vergata University of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark
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PO-21 | Evaluating the impact of anti-CGRP monoclonal antibodies on retinal features in migraine patients: a retrospective optical coherence tomography study Chiara Serafini,1 Massimo Cesareo,2 Alessio Martucci,2 Marco Lombardo,2 Vittoria Carla D’Agostino,1 Alessandro Stefani,3 Carlo Nucci,2 Nicola Biagio Mercuri,1,3 Maria Albanese1,3 | 1Regional Referral Headache Center, Neurology Unit, Tor Vergata University Hospital, Rome, Italy 2Ophthalmology Unit, Department of Experimental Medicine, University of Rome “Tor Vergata”, Rome; 3Department of Systems Medicine, University of Rome “Tor Vergata”, Rome, Italy
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PO-40 | Evaluating agreement between physician and ChatGPT in migraine prophylaxis selection: a pilot comparative study Simone Vigneri1, MatteoZanella2, Gianfranco Sindaco2, Alberto Merlin2, Maria Mazzullo2, Marco La Grua2, Valentina Paci2, Carmen Bertone2, Gilberto Pari2 1Santa Maria Maddalena Hospital, Neurology, Occhiobello, Italy; 2Santa Maria Maddalena Hospital, Pain Medicine, Occhiobello, Italy
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PO-92 QZU® (Kudzu e.s.: 200 mg of which Isoflavones: 80 mg and Puerarin: 60 mg; ComplexZyme vegan®: 40 mg) in the prophylaxys of migraine without aura: a retrospective observational study Ennio Pucci,1 Ludovica Pucci,2 Alberto Vercesi3 | 1Department of Nervous System and Behavioral Sciences, University of Pavia; 2Nutritional biologist, Master in Nutritional and Clinical Dietetics, University of Pavia, Italy; 3Scientific Advisor
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PO-27 | A monitoring of intracranial hypertension through the valuation of optic nerve sheath diameter with bedside ultrasounds. A case report Antonio Taglialatela,1 Camilla Gaiga,1 Simone Lorenzut,2 Enrico Belgrado,2 Mariarosaria Valente1,3 | 1Clinical Neurology Unit, Department of Head, neck and neurosurgery, Udine University Hospital, Udine; 2Neurology Unit, "Head, Neck and Neurosciences" Department, University Hospital of Udine; 3Department of Medical Area, University of Udine, Udine, Italy
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PO-14 | Pain catastrophizing in chronic migraine patients receiving eptinezumab treatment Alessandra Parisi,1 Licia Grazzi,1 Alberto Raggi,2 Giulia Regonesi,1 Montisano Danilo Antonio1 | 1Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano; 2Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy
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OC-06 | Migraine in the elderly: a retrospective study in a tertiary headache center Giulia Paparella,1,2 Stefania Scannicchio,1 Annalisa Di Dio,1 Emmanuella Ladisa,1 Chiara Abbatantuono,1 Elena Ammendola,1 Katia Ricci,1 Giusy Tancredi,1 Livio Clemente,1 Marianna Diletta Delussi,3 Marina de Tommaso1 | 1Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro, Bari; 2IRCCS Neuromed, Pozzilli (IS; 3Department of Education, Psychology, Communication (For.Psi.Com.), University of Bari Aldo Moro, Bari, Italy
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PO-33 | Visual hallucinations: a non-unique symptom Francesca Traccitto, Giada Giuliani, Davide Chiffi, Chiara Zilli, Mariangela Fratino, Marta Altieri | Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy
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“In principio era il Verbo”. Il ruolo della parola tra neurologia e psicoanalisi, da Jean-Martin Charcot (1825-1893) a Jacques Lacan (1901-1981) Il ruolo della parola tra neurologia e psicoanalisi.
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OC-12 | The potential role of sleep quality in the relationship between glymphatic function and migraine frequency: insights from a cross-sectional study Maria Grazia Vittorini, Raffaele Ornello, Federico Salfi, Antonio Innocenzi, Federico De Santis, Federico Bruno, Francesca Pistoia, Michele Ferrara, Alessandra Splendiani, Simona Sacco | Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, Italy
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PO-07 | Psychological management of children treated at the Pediatric Headache Centre of Turin: preliminary analysis Emanuela Serri, Annachiara Lamberti Zanardi, Raffaella Mascolo, Barbara Lauria, Roberta Rossi, Sara Simona Racalbuto, Antonia Versace, Claudia Bondone | Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin, Italy
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PO-91 | Real-world evidence of CGRP dual blockade: clinical and biomarker insights from combined therapy in chronic migraine Laura Marino,1 Marta Lioi1, Rosario Iannacchero,2 Michele Trimboli2 | 1Department of Neurology, Magna Graecia University, Catanzaro; 2Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-26 | Optic nerve sheath ultrasound in idiopatic intracranial hypertension: early findings Francesca Cotichelli,1,2 Davide Mascarella1,1,2 Valentina Favoni,1 Gaia Patanè,1,2 Francesco Severi,1,2 Francesca Verna,1,2 Giulia Pierangeli,1,2 Sabina Cevoli1 | 1IRCCS Istituto delle Scienze Neurologiche di Bologna; 2DIBINEM, Department of Biomedical and Neuromotor Science, Alma Mater Studiorum, Bologna, Italy
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PO-45 | Botulinum toxin in clinical practice: a turning point for chronic migraine and MOH Chiara Zilli, Davide Chiffi, Giada Giuliani, Francesca Traccitto, Mariangela Fratino, Marta Altieri | Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy
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PO-13 | HD-EEG Delta connectivity rapidly alters after one month of atogepant in migraine patients Maria Albanese,1,2 Matteo Conti,1 Silvio Bagetta,1 Federico Carparelli,2 Vittoria Carla D’Agostino,2 Fabio Placidi,1,2 Alessandro Stefani,1,2 Nicola Biagio Mercuri,1-3 | 1Department of Systems Medicine, University of Rome Tor Vergata, Rome; 2Neurology Unit, Tor Vergata University Hospital, Rome; 3IRCCS Santa Lucia Foundation, Rome, Italy
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OC-24 | A retrospective case-control study aimed at analyzing, through the administration of a questionnaire, the prevalence, clinical features and the risk factors for chronicity in a sample of 419 pediatric patients Alice Bonuccelli, Sara Mundo, Emma Iacopelli, Alessandro Orsini, Lorenza Marini, Diego Peroni | Neuropediatric, Pediatric Clinic, AOU Pisa, Italy
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PO-51 | Rimegepant combined with valproic acid and botulinum toxin in refractory hemiplegic migraine: a case report Gianni Difonzo, Cinzia Tamborino, Adriana Fallacara, Damiano Paolicelli, Maria Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy
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PO-19 | Unraveling the spectrum of migraine resistant to treatments: searching for novel biological PHEnotypes and theRApeutic approaches (SPHERA project) M. Giraudo,1,2 R. De Icco,1,2 G. Vaghi,1,2 V. Grillo,1,2 F. Bighiani,1,2 M. Corrado,2 A. Antoniazzi,1,2 F. Cammarota,1,2 B. Agostini,1,2 A. Solfrizzi,1,2 M. Allena,2 E. Guaschino,2 N. Ghiotto,2 R. Greco,2 C. Demartini,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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OC-11 | Corneal nerve plexus impairment in patients with trigeminal neuralgia Daniel Litewczuk,1 Gianfranco De Stefano,1 Sabrina Compagno,2 Mattia D’Andrea,2 Ludovico Alisi,2 Marco Marenco,2 Giulia Di Stefano,1 Andrea Truini1 | 1Department of Human Neuroscience, Sapienza University of Rome, 2Department of Sense Organs, Sapienza University of Rome, Italy
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PO-06 | Children’s headache through drawings: a narrative review and a portrait gallery Floriana Ferro,1,2 Caterina Gaspari,1,2 Giulia Manfrè,1,2 Federica Cernigliaro,1 Daniela D’Agnano,3 Ruben Panzica,4 Edvige Correnti,2 Maria Rosita Ruta,5 Francesca Marchese,5 Renata Pitino,2 Maria Rita Capizzi,2 Giuseppe Santangelo,2 Antonella Versace,6 Vittorio Sciruicchio,3 Vincenzo Raieli2 | 1Child Neuropsychiatry Unit Department, Pro.MI.S.E. "G. D'Alessandro", University of Palermo; 2Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo; 3Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari, Bari; 4Rheumatology Unit, Department of Clinical and Experimental Medicine, University of Messina; 5Child Neuropsychiatry Unit, ASP 6, Palermo; 6Pediatric Headache Center, Pediatric Emergency Dept, Regina Margherita Children's Hospital, Turin, Italy
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PO-90 | CAPSULASE® (PEA (palmitoylethanolamide), PHYTOSOME (quercetin from Sophora japonica L. 40% soy lecithin, microcrystalline cellulose, aerosil), CASPEROME (Boswellia serrata R., gum resin 40%, soy lecithin, microcrystalline cellulose, aerosil), bromelain 2 Ennio Pucci,1 Ludovica Pucci,2 Alberto Vercesio3 | 1Department of Nervous System and Behavioral Sciences, University of Pavia; 2Nutritional biologist, Master in Nutritional and Clinical Dietetics, University of Pavia, Italy; 3Scientific Advisor
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PO-25 | Antiepileptic medication in PRRT2 familial hemiplegic migraine: a case report L. Bartole, A. Granato, G. Garascia, P. Manganotti | Clinical Unit of Neurology, Headache Centre, Department of Medicine, Surgery and Health Sciences, University of Trieste, Italy
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PO-77 | Real-world evidence of Atogepant efficacy in patients unresponsive to anti-CGRP monoclonals Matteo Cortinovis, Marco Bolchini, Paola Zavarise, Giulia Campana, Giorgio Dalla Volta | Headache Center, Istituto Clinico Città di Brescia, Gruppo San Donato, Brescia, Italy
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PO-12 | The long-term efficacy on migraine of non-ketogenic low-carb diet after treatment with ketogenic diet Silvia Favaretto,1 Francesco Francini Pesenti2 | 1Headache centre, Neurology Unit, Department of Neuroscience, University Hospital of Padua; 2Department of Medicine (DIMED), Clinical Nutrition, University Hospital of Padua, Italy
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PO-64 | Telemedicine in a second level headache clinic of Azienda Sanitaria Locale Roma 1: a lesson learned from the SarsCov2 pandemic Teresa Catarci | ASL Roma 1, Rome, Italy
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PO-31 | Could lamotrigine represent an effective treatment strategy in patients with migraine with aura? An observational study M. Marziani, M. Silvestro, I. Orologio, L. Tartaglione, F.M. Chianese, A. Tessitore, A. Russo | Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Italy
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PO-18 | A clinical guide to assess and manage altered pain sensitivity and cervical musculoskeletal impairments migraine patients. Part 2: individualised treatment Matteo Castaldo,1,2 Lars Arendt-Nielsen,1 Stefano Di Antonio1,3 | 1Department of Health Science and Technology, Center for Pain and Neuroplasticity (CNAP), SMI, School of Medicine, Aalborg University, Aalborg, Denmark; 2Department of Medicine and Surgery, Clinical Psychology, University of Parma; 3Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics and Maternal Child Health, University of Genoa, Italy
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OC-10 | Assessing white matter hyperintensities in cluster headache: a distinct pathophysiological profile compared to migraine G. Giuliani,1 A. Viganò,2 C. Zilli,1 D. Chiffi,1 E. Vicenzini,1 V. Di Piero,1 M. Altieri1 | 1Department of Human Neuroscience, Sapienza University of Rome; 2IRCCS Fondazione Don Carlo Gnocchi, Milan, Italy
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PO-37 | Trigeminal autonomic cephalalgia as the initial presentation of a cerebral cavernous malformation: a rare case report Francesco Maurizio Chianese, Marcello Silvestro, Ilaria Orologio, Lorenzo Tartaglione, Marcella Marziani, Antonio Russo | Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy
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PO-89 | Alcohol and headache: an update Alessandro Panconesi,1,2 Maria Letizia Bartolozzi1 | 1Headache Centre, Department of Neurology, Health Authority, Empoli; 2Clinical Research Institute Ecomedica, Empoli, Italy
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OC-16 | Network-level brain connectivity alterations in an animal model of migraine and the effects of olcegepant treatment Rosaria Greco,1 Gloria Castellazzi,1 Miriam Francavilla,1,2 Chiara Demartini,1 Sara Facchetti,1,2 Daniele Martinelli,1 Cristina Tassorelli1,2 | 1Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 2Department of Brain and Behavioral Sciences, University of Pavia, Italy
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PO-43 | Eptinezumab in migraine patients unresponsive to prior subcutaneous CGRP(-R) monoclonal antibody treatment: a retrospective case series Elena Cresta, Irene Mattioli, Michele Di Pasquale, Alice Lanfranchi, Renata Rao, Alessandro Padovani | Neurology Unit and Headache Centre, Dipartimento di continuità di cura e fragilità, ASST Spedali Civili e Università degli studi di Brescia, Brescia, Italy
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PO-11 | Resting state high-density EEG analysis reveals interictal subcortico-cortical linear and non-linear anomalies in subjects with migraine Gabriele Sebastianelli,1 Camillo Porcaro,2 Sara Gilli,1 Chiara Abagnale,1 Francesco Casillo,2 Giorgio Di Lorenzo,3 Gianluca Coppola1 | 1Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino ICOT, Latina; 2Department of Neuroscience (DNS) and Padova Neuroscience Center (PNC), University of Padova; 3Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Italy
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