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PO-09 | When migraine turns severe: a case of aura that lasts too long Alessandra Fera,1 Erica Agosto,1 Giulia Grasso,2 Cristina Vassia,2 Francesca Feyles,2 Carlotta Canavese,3 Sara Racalbuto,2 Antonia Versace2 | 1Department of Public Health and Pediatrics, University of Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin; 3Department of Child Pathology and Care “Regina Margherita”, SSD Pediatric Neurology, Regina Margherita Children’s Hospital, Turin, Italy
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PO-55 | What patients want: a qualitative study on an information resource on migraine Matteo Castaldo,1 Zhiqi Liang,2 Gina Williams,2 Shayne Watson,2 Caitlyn Haynes,2 Zoe Diamond2 | 1Parma University; 2University of Queensland
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PO-33 | Visual hallucinations: a non-unique symptom Francesca Traccitto, Giada Giuliani, Davide Chiffi, Chiara Zilli, Mariangela Fratino, Marta Altieri | Department of Human Neuroscience, Sapienza University of Rome, Rome, Italy
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PO-05 | Validation of the Italian version of the HARDSHIP Questionnaire in a school-based population Agnese Onofri,1 Chiara Rosignoli,1 Vittorio Trozzi,1 Martina D’Ambrosio,1 Benedetta Germani,1 Roberta Ciuffini,2 Raffaele Ornello,1 Simona Sacco1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Clinical Medicine, Public health, Life and Environmental Sciences, University of L’Aquila, Italy
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PO-19 | Unraveling the spectrum of migraine resistant to treatments: searching for novel biological PHEnotypes and theRApeutic approaches (SPHERA project) M. Giraudo,1,2 R. De Icco,1,2 G. Vaghi,1,2 V. Grillo,1,2 F. Bighiani,1,2 M. Corrado,2 A. Antoniazzi,1,2 F. Cammarota,1,2 B. Agostini,1,2 A. Solfrizzi,1,2 M. Allena,2 E. Guaschino,2 N. Ghiotto,2 R. Greco,2 C. Demartini,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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PO-37 | Trigeminal autonomic cephalalgia as the initial presentation of a cerebral cavernous malformation: a rare case report Francesco Maurizio Chianese, Marcello Silvestro, Ilaria Orologio, Lorenzo Tartaglione, Marcella Marziani, Antonio Russo | Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania "Luigi Vanvitelli", Naples, Italy
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PO-35 | Treatment of chronic and episodic migraine with atogepant improves quality of life in patients with comorbid multiple sclerosis: the experience of the Headache Center at Spaziani Hospital, Frosinone Laura Borrello; Fabiana Marinelli; Maria Lorena Marziale; Ilaria Avallone; Fulvio Ferrante; Roberto De Simone | Neurology Unit, Headache Center, Multiple Sclerosis Center, UOC Pharmacy, Spaziani Hospital, Frosinone (FR), Italy
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PO-69 | Three-month atogepant treatment modulates dopaminergic-related functional connectivity in episodic migraine Davide Fedeli,1 Danilo Antonio Montisano,1 Greta Demichelis,1 Giuseppe Ciullo,1,2 Jean Paul Medina Carrion,1 Maria Grazia Bruzzone,1 Emilio Ciusani,1 Alessandra Erbetta,1 Marina Grisoli,1 Erika Guastafierro,1 Domenico D’Amico,1 Alberto Raggi,1 Anna Nigri,1 Licia Grazzi1 | 1Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy; 2University of Parma, Parma, Italy
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PO-56 | The role of bilateral greater occipital nerve block in resistant chronic migraine with medication overuse Leonardo Troilo, Letizia Curto, Giulia Procopio, Antonia Di Chirico, Gabriele Siciliano, Sara Gori, Filippo Baldacci | Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa-AOUP, Pisa, Italy
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PO-12 | The long-term efficacy on migraine of non-ketogenic low-carb diet after treatment with ketogenic diet Silvia Favaretto,1 Francesco Francini Pesenti2 | 1Headache centre, Neurology Unit, Department of Neuroscience, University Hospital of Padua; 2Department of Medicine (DIMED), Clinical Nutrition, University Hospital of Padua, Italy
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PO-65 | The complexity of chronic headache: towards tailored therapies through a multidimensional assessment Silvia Favaretto,1 Giulia Demo,2 Veronica Rizzato,2 Elisabetta Patron,2,3,4 Sara Bianconi,2 Stèphanie Maldera,2 Giulia Buodo,2,3 | 1UOC Clinica Neurologica, Azienda Ospedale-Università Padova, Padua, Italy; 2Centro di Ateneo Servizi Clinici Universitari Psicologici (SCUP), University of Padua, Italy; 3Department of General Psychology, University of Padua, Padova, Italy; 4Padua Neuroscience Center (PNC), University of Padua, Padova, Italy
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PO-64 | Telemedicine in a second level headache clinic of Azienda Sanitaria Locale Roma 1: a lesson learned from the SarsCov2 pandemic Teresa Catarci | ASL Roma 1, Rome, Italy
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PO-47 | Systemic ozone treatment in chronic migraine: a focus on disability reduction and medication use Sergio Sorrenti,1,2 Matteo Ciuffreda,1 Emanuele Pisello,1 Luca Brugiaferri,2 Azzurra Federici,2 Cristiano Piangatelli,3 Dario Galante4 | 1U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 2Scuola di Specializzazione in Anestesia Rianimazione, Terapia Intensiva e del Dolore, UNIVPM, Ancona, Italy; 3Direttore U.O.C. Anestesia Rianimazione Terapia del Dolore, AST Ancona, Fabriano (AN), Italy; 4Direttore U.O.C. Anestesia e Rianimazione, Cerignola (FG), Italy
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PO-79 | Survey on adherence and tolerability of atogepant used as migraine preventive treatment D.A. Montisano,1 G. Vaghi,2,3 A. Paris,1 R. De Icco,2,3 B. Agostini,2,3 M. Giraudo,2,3 A. Solfrizzi,2,3 C. Tassorelli,2,3 G. Sances,3 L. Grazzi | 1Fondazione IRCCS C.Besta Istituto Neurologico, SSD Headache Center, Milan, Italy; 2University of Pavia, Department of Brain and Behavioral Sciences, Pavia, Italy; 3IRCCS Mondino Foundation, Headache Science & Neurorehabilitation Unit, Pavia, Italy
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PO-72 | Stigma in migraine: preliminary results from the “Studio Emicrania Maugeri” Project Luca Giani, Christian Lunetta | Istituti Clinici Scientifici Maugeri IRCCS, Neurological Rehabilitation Unit of Milano Institute, Milan, Italy
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PO-29 | Spontaneous intracranial hypotension: a clinical and radiological observational study F. Verna, D. Mascarella, V. Favoni, G. Pierangeli, L. Cirillo, S. Cevoli | IRCCS Istituto delle Scienze Neurologiche di Bologna, Italia DIBINEM, Alma Mater Studiorum Bologna, Italy
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PO-61 | Social cognition in interictal episodic and chronic migraine: a cross-sectional study Chiara Abbatantuono,1* Delussi Marianna,2* Clemente Livio,1 Giulia Paparella,1 Stefania Scannicchio,1 Annalisa Di Dio,1 Elena Ammendola,1 Giusy Tancredi,1 Emmanuella Ladisa,1 Giulia Paparella,1,3 Marina de Tommaso1 (*Equally Contributed) | 1Neurophysiopathology Unit, Department of Translational Biomedicine and Neuroscience (DiBraiN), University of Bari Aldo Moro (IT), Bari, Italy; 2Department of Education, Psychology, Communication (For.Psi.Com.), University of Bari Aldo Moro (IT), Bari, Italy; 3IRCCS Neuromed Pozzilli (IS), Italy
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PO-28 | Sex differences in the response to rimegepant for the treatment of acute migraine attacks – insights from the multicenter GAINER study Raffaele Ornello,1 Gloria Vaghi,2,3 Gabriele Sebastianelli,4 Francesco Casillo,4 Antonio Russo,5 Marcello Silvestro,5 Francesca Pistoia,1 Giorgio Dalla Volta,6 Matteo Cortinovis,6 Alberto Chiarugi,7 Danilo Antonio Montisano,8 Licia Grazzi,8 Maria Pia Prudenzano,9 Sabina Cevoli,10 Edoardo Mampreso,11 Gianluca Avino,12 Marina Romozzi,13 Mariarosaria Valente,14 Carla Fasano,15 Stefania Battistini,16 Antonio Granato,17 Elisa Maria Piella,18 Innocenzo Rainero,18 Federico De Santis,1 Simona Sacco,1 Maria Albanese,19 Michele Trimboli,20 Alberto Doretti,21 Cristina Tassorelli,2,3 Luigi Francesco Iannone,22 Roberto De Icco2,3 on behalf of the Italian Headache Registry (RICe) Study Group | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila; 2Department of Brain and Behavioral Sciences, University of Pavia; 3Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia; 4Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina; 5Headache Centre, Department of Advanced Medical and Surgical Sciences, University of Campania “Luigi Vanvitelli”, Naples; 6Headache Center of Clinical Neurology of Istituto Clinico "Città di Brescia", Brescia; 7Department of Health Sciences, University of Florence; 8Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan; 9Headache Center, Department of Basic Medical Sciences, Neurosciences and Sense Organs, University of Bari; 10IRCCS Istituto Di Scienze Neurologiche di Bologna, Programma Cefalee e Algie Facciali, Bologna; 11Headache Centre, Neurology - Euganea, Health Unit, Padua; 12Neurology Unit, Ospedale Santo Stefano, USL Toscana Centro, Prato; 13Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Università Cattolica del Sacro Cuore, Rome; 14Clinical Neurology, Azienda Sanitaria Universitaria Friuli Centrale, Presidio Ospedaliero Santa Maria della Misericordia, Udine; 15Headache and Facial Pain Center Neurology, AOU Careggi, Florence; 16Department of Medical, Surgical and Neurological Sciences, University of Siena; 17Headache Centre, Clinical Unit of Neurology, School of Neurology, Department of Medicine, Surgery and Health Sciences, University Hospital and Health Services of Trieste, ASUGI, University of Trieste; 18Department of Neurosciences “Rita Levi Montalcini”, University of Turin; 19Department of Systems Medicine, University of Rome Tor Vergata, Rome; 20University Magna Graecia, Catanzaro; 21Department of Neuroscience - Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan; 22University of Modena and Reggio Emilia, Modena, Italy
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PO-83 | Serum diamine oxidase activity in patients with cluster headache: a cross-sectional case–control study Silvia Boschi,1 Elisa Maria Piella,1 Tilde Manetta,3 Paola Merlach,3 Alberto Mario Chiarandon,1 Alessia Agostinelli,1 Barbara Donati Morello,3 Giulio Mengozzi,3 Innocenzo Rainero,1,2 Elisa Rubino,1,2 | 1Department of Neuroscience “Rita Levi Montalcini”, University of Turin, Turin, Italy; 2Headache Center, Department of Neuroscience and Mental Health, AOU Città della Salute e della Scienza di Torino, Turin, Italy; 3Department of Laboratory Medicine, Città della Salute e della Scienza University Hospital, Turin, Italy
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PO-51 | Rimegepant combined with valproic acid and botulinum toxin in refractory hemiplegic migraine: a case report Gianni Difonzo, Cinzia Tamborino, Adriana Fallacara, Damiano Paolicelli, Maria Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy
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PO-11 | Resting state high-density EEG analysis reveals interictal subcortico-cortical linear and non-linear anomalies in subjects with migraine Gabriele Sebastianelli,1 Camillo Porcaro,2 Sara Gilli,1 Chiara Abagnale,1 Francesco Casillo,2 Giorgio Di Lorenzo,3 Gianluca Coppola1 | 1Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Polo Pontino ICOT, Latina; 2Department of Neuroscience (DNS) and Padova Neuroscience Center (PNC), University of Padova; 3Chair of Psychiatry, Department of Systems Medicine, Tor Vergata University of Rome, Italy
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PO-91 | Real-world evidence of CGRP dual blockade: clinical and biomarker insights from combined therapy in chronic migraine Laura Marino,1 Marta Lioi1, Rosario Iannacchero,2 Michele Trimboli2 | 1Department of Neurology, Magna Graecia University, Catanzaro; 2Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-77 | Real-world evidence of Atogepant efficacy in patients unresponsive to anti-CGRP monoclonals Matteo Cortinovis, Marco Bolchini, Paola Zavarise, Giulia Campana, Giorgio Dalla Volta | Headache Center, Istituto Clinico Città di Brescia, Gruppo San Donato, Brescia, Italy
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PO-80 | Real-world effectiveness of atogepant for the preventive treatment of migraine in a cohort of multi -refractory patients: a single center study M. De Luca,1 L. Ferraù,1 A. Cafarchio,2 M.S. Adragna,1 M. Autunno1 | 1Unit of Neurology and Neuromuscular Diseases, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy; 2Department of Medicine and Health Sciences “Vincenzo Tibero” DIMES, University of Molise, Campobasso, Italy
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PO-92 QZU® (Kudzu e.s.: 200 mg of which Isoflavones: 80 mg and Puerarin: 60 mg; ComplexZyme vegan®: 40 mg) in the prophylaxys of migraine without aura: a retrospective observational study Ennio Pucci,1 Ludovica Pucci,2 Alberto Vercesi3 | 1Department of Nervous System and Behavioral Sciences, University of Pavia; 2Nutritional biologist, Master in Nutritional and Clinical Dietetics, University of Pavia, Italy; 3Scientific Advisor
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PO-59 | Questioning online survey-based physiotherapy treatment referral in headache treatment: differences in developed and developing countries D. Onan,1,2 A.K. Erdemoğlu,3 P. Gelener,4 S. Velioğlu,5 S. Ulutaş,6 N. Taşdemir,7 M. Waliszewska-Prosół,8 E. Ekizoğlu,9 M. Straburzyński,10 M. Kodounis,11 B. Raffaelli,12 C. Tana,13 F. De Cesaris,14 R. Messina,15 E.I. Sen,16 S. Ray,17 G. Sebastianelli,18 F. Granella,19 U. Pensato,20 S. Crema,21 S. Cevol,22 K. Chakravarty,23 M. Pia Prudenzano,24 A. Casalena,25 M. Romozzi,26 T. Takizawa,26 W. Rattanawong,27 A. Gantenbein,28 V. Favoni,29 C. Gaul,30 L.F.I. Iannone,31 B. Schäfer,23 D.A. Montisano,33 O. Grosu,34 A.B. de Oliveira,35 F. Puledda,36 V. Romanenko,37 I. Ros González,38 M. Castaldo,39 H. Al-Khazali,40 A. Hassan,41 D. Garcia-Azorin,42 L.-L. Hope Pan,43 R. Gil-Gouveia,44 M. Sanchez del Rio,45 M. Lisicki,46 H.W. Schytz,47 P. Anukoolwittaya,48 T. Mavridis,49 M. Lanteri-Minet,50 D.B. Swerts,51 C. Altamura,52 K. Hirata,53 M. Togha,54 M. Kyung Chu,55 T. Pongpitakmetha,56 M.-H. Bjørk,57 M. Minen,58 K. Skorobogatykh,59 D. Chowdhury,60 A.-M. Torgersen Dalgeir,61 J. Versijpt,62 P. Cras,63 A. Govaerts,64 A. Chiarugi,65 N. Vashchenko,59 L. Dobbels,66 T.S. Monteith,67 F. De Bruyne,68 E. Garay,67 S.L. Sava,69 Z. Salinas,67 M. Nordtveit,70 K. Delmotte,71 A. Gonzalez-Martinez,72 S. Debray,73 C. Deligianni,74 W. De Hertogh,75 R. Castien,76 E. Caronna,77 C. Valerija,78 F. Ahmed,79 G. De la Meilleure,80 L.L. Panneerchelvam,81 G.H. Bringeland,82 R. Ornello,2 S. Sacco2 | 1Yozgat Bozok University, Physiotherapy and Rehabilitation, Ankara, Turkey;2University of L'Aquila, Department of Biotechnological and Applied Clinical Sciences, L'Aquila, Italy;3Clinic of Prof. Dr. Ali Kemal Erdemoğlu, Neurology, Ankara, Turkey;4Elite Research and Surgical Hospital , Nicosia, Cyprus;5Karadeniz Technical University, Department of Neurology, Trabzon, Turkey;6Bahcesehir University, Department of Neurology, İstanbul, Turkey;7Ağrı İbrahim Çeçen University, Department of Neurology, Ağrı, Turkey;8Wroclaw Medical University, Wroclaw, Germany;9Istanbul University, Department of Neurology, Istanbul, Turkey;10University of Warmia and Mazury, Olsztyn, Poland;11National & Kapodistrian University of Athens, First Neurology Department, Eginitio Hospital, School of Medicine, Athens, Greece;12Charité Universitätsmedizin Berlin, Department of Neurology,Headache Center, Berlin, Germany;13SS Annunziata Hospital of Chieti, Chieti, Italy;14Centro Cefalee e Farmacologia Clinica - AOU Careggi , Florence, Italy;15Vita-Salute San Raffaele University, Milano, Italy;16Istanbul University Istanbul Faculty of Medicine, Department of Physical Medicine and Rehabilitation, İstanbul, Turkey;17Department of Neurology, PGIMER, Chandigarh, India;18Sapienza University of Rome, Latina, Italy;19University of Parma, Parma, Italy;20Humanitas University, Milan, Italy;21Fleni Hospital, Buenos Aires, Argentina;22University of Bologna, Bologna, Italy;23Post Graduate Institute Of Medical Education and Research, Chandigarh, India;24AOUC Policlinico, Centro Cefalee - Clinica Neurologica L Amaducci, Bari, Germany;25Centro Cefalee UOC Neurologia, Teramo, Italy;26Keio University School of Medicine, Tokyo, Japan;27King Mongkut's Institute of Technology Ladkrabang, Bangkok, Thailand;28ZURZACH Care, Zürich, Switzerland;30IRCCS Istituto delle scienze neurologiche di Bologna, Bologna, Italy;30Headache Center Frankfurt, Frankfurt, Germany;31Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Modena, Italy, Modena, Italy;32Migraine and Headache Clinic Königstein , Frankfurt, Germany;33SSD Centro Cefalee - Fondazione IRCCS Istituto Neurologico C.Besta, Milan, Italy;34Diomid Gherman Institute of Neurology and Neurosurgery, Kişinev, Moldova;35Center for Clinical and Epidemiological Research, University of Sao Paulo , Sao Paolo, Brazil;36King's College London, London, United Kingdom;37Vita Medical Clinic, Kyiv, Ukraine;38Hospital Clínico Universitario de Valladolid, Vallodolid, Spain;39Parma University, Parma, Italy;40Danish Headache Center, Copenhagen, Denmark;41Cairo University , Cairo, Egypt;42University of Valladolid, Valladolid, Spain;43Brain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan;44Hospital da Luz. Lisboa, Lisboa, Portugal;45Clinica Universidad de Navarra, Navarra, Spain;46Mercedes & Martín Ferreyra Institute for Medical Research, Córdoba, Argentina;47University of Copenhagen, Copenhagen, Denmark;48King Chulalongkorn Memorial Hospital, Bangkok, Thailand;49Tallaght University Hospital, Dublin, Ireland;50CHU Nice and Cote D'azur University, Nice, France;51Santa Casa de Sao Paolo, Sao Paolo, Brazil;52Fondazione Policlinico Universitario Campus BIo-Medico, Rome, Italy;53Dokkyo Medical University, Mibu, Tochigi, Japan;54Tehran University, Tehran, Iran;55Yonsei University, Seoul, South Korea;56Chulalongkorn University, Bangkok, Thailand;57University of Bergen , Bergen, Norway;58NYU Langone Health, New York, United States;59University Headache Clinic, Moscow, Russian Federation;60 G B Pant Institute of Post Graduate Medical Education and Research, New Delhi, India;61Haukeland University Hospital, NorHead, Bergen, Norway;62UZ Brussel, Brussel, Belgium;63Universiteit Antwerpen, Antwerpen, Belgium;64Rz Tienen, Tienen, Belgium;65University of Florence, Florence, Italy;Neurology Department İmelda Ziekenhuis, Bonheiden, Belgium;67University of Miami, Miami, United States;68University College Ghent, Ghent, Belgium;69University of Liège, Liege, Belgium;70Haukeland Universitetssykehus, Bergen, Norway;71Universitair Ziekenhuis Leuven, Leuven, Belgium;72Hospital Universitario de la Princesa e Instituto de Investigación Sanitaria Princesa, Madrid, Spain;73Europa Ziekenhuizen, Brussel, Belgium;74Athens Naval Hospital, Athens, Greece;75University of Antwerp , Antwerpen, Belgium;76Vrije Universiteit Amsterdam, Amsterdam, Netherlands;77Vall d'Hebron Hospital, Barcelona, Spain;78Private hospital, Riga, Latvia;79Hull University, Hull, United Kingdom;80VITAZ - General Hospital, Sint-Niklaas, Belgium;81James Cook University Hospital, Middlesbrough, United Kingdom; 82Haukeland University Hospital, Bergen, Norway
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PO-07 | Psychological management of children treated at the Pediatric Headache Centre of Turin: preliminary analysis Emanuela Serri, Annachiara Lamberti Zanardi, Raffaella Mascolo, Barbara Lauria, Roberta Rossi, Sara Simona Racalbuto, Antonia Versace, Claudia Bondone | Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin, Italy
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PO-62 | Preventive migraine treatment in patients under 25: a 24-month observational study on adherence, therapeutic switching, and prescription determinant factors Marilena Marcosano,1 Nicoletta Brunelli,1 Luisa Fofi,1 Laura Papetti,2 Fabiana Ursitti,2 Massimiliano Valeriani,2 Fabrizio Vernieri,1 Claudia Altamura1 | 1Headache and Neurosonology Unit, Fondazione Policlinico Campus Biomedico di Rome, Rome, Italy; 2Developmental Neurology, Bambino Gesù Children Hospital, IRCCS, Rome, Italy
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PO-66 | Predicting the evolution to resistant and refractory migraine: a machine learning analysis from the REFINE Study Chiara Rosignoli,1 Raffaele Ornello,1 Daniele Lozzi,2 Enrico Mattei,2 Federico De Santis,1 Agnese Onofri,1 Mark Braschinsky,3 Christian Lampl,4 Isabel Pavão Martins,5 Paolo Martelletti,6 Dimos Mitsikostas,7 Raquel Gil-Gouveia,8 Maria Pia Prudenzano,9 Kristina Ryliskiene,10 Margarita Sanchez del Rio,11 Patricia Pozo-Rosich,12 Aynur Özge,13 Fabrizio Vernieri,14 Marta Waliszewska-Prosół,15 Zaza Katsarava,16 Giuseppe Placidi,2 Simona Sacco1 | 1Dept. of Biotechnological and Applied Clinical Sciences, University of L'Aquila, Italy; 2A²VI-lab, Dept. MeSVA University of L’Aquila; 3Dept. of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu, Estonia; 4Headache Medical Center, Seilerstaette Linz, Austria. Center; 5Headache Center, Hospital da Luz, Lisbon, Portugal; 6School of Health, Unitelma Sapienza University of Rome, Italy; 7First Dept of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Greece; 8Centro de Estudos Egas Moniz, Faculty of Medicine, University of Lisbon, Portugal; 9Headache Center, Amaducci Neurological Clinic, Policlinico General Hospital, Bari, Italy; 10Center of Neurology, Vilnius University, Lithuania; 11Dept. of Neurology, Clínica Universidad de Navarra, Madrid, Spain; 12Neurology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain; 13Dept. of Neurology, Mersin University Medical Faculty, Mersin, Turkey; 14Università Policlinico Campus Bio-Medico, Rome, Italy; 15Dept. of Neurology, Wroclaw Medical University, Wrocław, Poland; 16Dept of Neurology, Christian Hospital Unna and University of Duisburg-Essen, Ruhr Metropolitan, Germany
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PO-32 | Post-traumatic painful trigeminal neuropathy (13.1.2.3 - ICHD-3) following misguided gamma knife surgery: a case of diagnostic oversight with lasting consequences Marta Lioi,1 Laura Marino,1 Michele Trimboli2 | 1Department of Neurology, Magna Graecia University, Catanzaro, Italy; 2Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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PO-58 | Pilot protocol to improve the booking and management network for chronic headache in secondary and tertiary care services A. Granato,1 L. Bartole,1 S. Centonze,2 A. Lodi,3 M. Lodi Zollia,3 P. Manganotti1 | 1Clinical Unit of Neurology, Headache Centre, Department of Medicine, Surgery and Health Sciences, ASUGI, University of Trieste, Trieste, Italy; 2Research & Innovation Unit, ASUGI, University of Trieste, Trieste, Italy; 3Funzione Organizzativa, Gestione Offerte Ambulatoriali, ASUGI, University of Trieste, Trieste, Italy
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PO-20 | Phenotypic description of a multigenerational family with PRRT2 gene mutation: a case series of six members affected by hemiplegic migraine and paroxysmal events Fabiana Cerulli,1 Costanza Sottani,1 Giulia Di Lazzaro,1,2 Paolo Calabresi,1,2 Anna Rita Bentivoglio,1,2 Catello Vollono1,3 | 1Dipartimento Universitario di Neuroscienze, Università Cattolica del Sacro Cuore, Rome; 2UOC Neurologia, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy; 3Neurofisiopatologia, Dipartimento di Scienze dell'invecchiamento, Neurologiche, Ortopediche e della Testa-Collo, Fondazione Policlinico Universitario "A. Gemelli" IRCCS, Rome, Italy
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PO-01 | Pediatric nummular headaches: a case series and physiopathological and nosography considerations Carola Meo¹*, Sofia D’Agostino¹*, Antonella Morea²*, Martina Tarantini²*, Giuseppe Giglia³, Maria Rosita Ruta⁴, Edvige Correnti⁵, Daniela D’Agnano², Giuseppe Santangelo⁵, Vittorio Sciruicchio², Vincenzo Raieli⁵ (*These authors contributed equally) | 1Child Neuropsychiatry Unit Department, Pro.M.I.S.E. "G. D'Alessandro", University of Palermo, Palermo, Italy; 2Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari, Bari, Italy; 3Department of Biomedicine, Neuroscience and Advanced Diagnostics (BIND), Section of Human Physiology, University of Palermo, Palermo; 4Child Neuropsychiatry Unit, ASP 6, Palermo; 5Child Neuropsychiatry Department, ISMEP, ARNAS Civico, Palermo, Italy
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PO-54 | Patient perspectives on physiotherapy interventions for migraine: a pre- and post-intervention qualitative study Zhiqi Liang,1 Caitlin Scott,1 Felix Cabrera Manrique,1 Sumin Kim,1 Chun Shun Lee,1 Bixiang Cheng,1 Chun Yiu Kwok,1 Matteo Castaldo2 | 1University of Queensland; 2Parma University, Italy
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PO-14 | Pain catastrophizing in chronic migraine patients receiving eptinezumab treatment Alessandra Parisi,1 Licia Grazzi,1 Alberto Raggi,2 Giulia Regonesi,1 Montisano Danilo Antonio1 | 1Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano; 2Neurology, Public Health and Disability Unit, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milano, Italy
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PO-26 | Optic nerve sheath ultrasound in idiopatic intracranial hypertension: early findings Francesca Cotichelli,1,2 Davide Mascarella1,1,2 Valentina Favoni,1 Gaia Patanè,1,2 Francesco Severi,1,2 Francesca Verna,1,2 Giulia Pierangeli,1,2 Sabina Cevoli1 | 1IRCCS Istituto delle Scienze Neurologiche di Bologna; 2DIBINEM, Department of Biomedical and Neuromotor Science, Alma Mater Studiorum, Bologna, Italy
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PO-42 | OnaBotulinumtoxin-A in chronic migraine patients with short or long disease history and psychiatric comorbidities: preliminary data from an Italian multicentric study (the BACH Study) Fabrizio Vernieri,1,2 Marilena Marcosano,2 Licia Grazzi,3 Danilo Antonio Montisano,3 Raffaele Ornello,4 Simona Sacco,4 Chiara Rosignoli,4 Alberto Doretti,5 Maria Albanese,6 Giovanna Viticchi,7 Nicoletta Brunelli, Luigi d’Onofrio,2 Luisa Fofi,1 Claudia Altamura,1,2 Patrizio Pasqualetti8 | 1Fondazione Policlinico Campus Bio-Medico, Roma, Italy; 2Università Campus Bio-Medico di Roma, Italy; 3Istituto Neurologico Besta, Milano, Italy; 4Università degli Studi l’Aquila, Italy; 5Istituto Auxologico, Milano, Italy; 6Policlinico Tor Vergata, Roma, Italy; 7Università Politecnica Marche, Italy; 8Sapienza Università di Roma, Italy
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PO-78 | No changes in blood pressure assessed with the 24-hour Holter monitoring in patients treated with anti-CGRP monoclonal antibodies: a prospective observational study (SAFHYPER) Flavia Lo Castro,1 Niccolò Bonini,2 Luigi Francesco Iannone,1,3 Alberto Boccalini,1 Daria Brovia,1 Luca Pani,1,3 Giuseppe Boriani,2,3 Simona Guerzoni1 | 1Digital and Predictive Medicine, Pharmacology and Clinical Metabolic Toxicology-Headache Center and Drug Abuse-Laboratory of Clinical Pharmacology and Pharmacogenomics, AOU Policlinico di Modena, Modena, Italy; 2Cardiology Division, AOU Policlinico di Modena, Modena, Italy; 3Department of Biomedical, Metabolic, and Neural Science, University of Modena and Reggio Emilia, Modena, Italy
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PO-16 | Neurophysiological effects of atogepant in high-frequency episodic migraine B. Agostini,1,2 F. Cammarota,1,2 R. De Icco,1,2 V. Grillo,1,2 G. Vaghi,1,2 F. Bighiani1,2, M. Corrado,2 A. Antoniazzi,1,2 M. Giraudo,1,2 A. Solfrizzi,1,2 R. Greco,2 C. Demartini,1,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy
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PO-75 | Network meta-analysis comparing efficacy and safety outcomes of atogepant, rimegepant, and galcanezumab in patients with episodic migraine after including CHALLENGE-MIG Trial Jessica Ailani,1 Pranav Gandhi,2 Anjana Lalla,2 Peter McAllister,3 Tanya Bilchik,4 Stephanie Nahas,5 David Rowe,6 Cristiano Piron,6 Kari Kelton,6 Raffaello Masselli*, Rashmi Halker Singh7 | 1MedStar Health, Washington DC, USA; 2AbbVie, North Chicago, IL, USA; 3New England Institute for Neurology and Headache, Stamford, CT USA; 4Department of Neurology, Yale School of Medicine, New Haven, CT, USA; 5Department of Neurology, Thomas Jefferson University, Philadelphia, PA USA; 6Medical Decision Modeling Inc., Indianapolis, IN, USA; 7Mayo Clinic, Phoenix, AZ, USA *Abbvie Srl, Rome, Italy. This individual has been added to this publication author by-line, with the permission of the original authors, for the express purpose of conducting the presentation at a local congress or in a local language. He did not contribute to the content of the publication.
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PO-04 | Mindfulness-based behavioral intervention for adolescents with high-frequency primary headaches: feasibility of a prospective multicenter study Beatrice Baldo,1 Giulia De Lorenzi,1 Valeria Marletta,1 Ilaria Bonemazzi,1 Alessia Raffagnato,2 Cristina Vassia,3 Emanuela Serri,3 Antonella Versace,4 Daniela D’Agnano,4 Vittorio Sciruicchio,4 Licia Grazzi,5 Irene Toldo1 | 1Juvenile Headache Center, Department of Woman’s and Child’s Health, University of Padua; 2Child and Adolescent Neuropsychiatric Unit, Department of Women's and Children's Health, University of Padua; 3Pediatric Headache Center, Department of Pediatric Emergency, Regina Margherita Children's Hospital, Turin; 4Children Epilepsy and EEG Center, San Paolo Hospital, ASL Bari; 5Neuroalgology Unit and Headache Center, Fondazione IRCCS Istituto Neurologico Carlo Besta, Milan, Italy
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PO-02 | Migraine in youth: a double challenge to cognition and emotion Samuela Tarantino,1 Martina Proietti Checchi,1 Laura Papetti,1 Fabiana Ursitti,1 Gabriele Monte,1 Giorgia Sforza,1 Massimiliano Valeriani,1-3 | 1Developmental Neurology Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy; 2Systems Medicine Department, Tor Vergata University of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark
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PO-53 | Managing chronic primaryhHeadache in Lombardy: insights from the ‘PERLA’ project Grazia Sances,1 Claudia Sulmona,1 Natascia Ghiotto,1 Daniele Martinelli,1 Licia Grazzi,2 Alberto Raggi,2 Danilo Antonio Montisano,2 Matilde Leonardi,2 Giulia Gandini,2 Renata Rao,3 Alessandro Padovani,3 Alessandro Amorosi,5 Cristina Tassorelli,1,5 on behalf of Rete Regionale Cefalee Lombardia | 1Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation Pavia, Italy; 2Headache Center, IRCCS Fondazione Istituto Neurologico Carlo Besta, Milan, Italy; 3ASST Spedali Civili di Brescia, Italy; 4Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy; 5Struttura Reti Clinico-Assistenziali e Organizzative e Ricerca, U.O. Polo Ospedaliero Direzione Generale Welfare, Regione Lombardia, Italy
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PO-08 | Long-term outcome in pediatric patients with headache S. Genta,1,2 M. Celario1,2, C. Brancaccio¹ ², G. Rossetto,1,2 C. Dusi,1,2 P. Baso,1,2 V. De Giorgis1,2 | 1Department of Child Neuropsychiatry, IRCCS Mondino, Pavia; 2University of Pavia, Italy
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PO-52 | Long-term efficacy of CGRP mAbs: new insights and current evidence Oreste Marsico,1 Marta Lioi,2 Rosario Iannacchero,3 Michele Trimboli3 | 1Department of Neuroscience, “Giovanni Paolo II” Hospital, Lamezia Terme, Catanzaro, Italy; 2Department of Neurology, Magna Graecia University, Catanzaro, Italy; 3Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy
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