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Confinia Cephalalgica

eISSN 3035-0670 | Official journal of the Italian Society for the Study of Headaches (SISC)

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Editor-in-Chief: Pierangelo Geppetti, Italy

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  • Unruly and unsubmissive. A historical approach to the condition of women in mental hospitals between the 19th and 20th centuries Approccio storico sulle condizioni delle donne negli ospedali psichiatrici

    Mariano Martini, Maria Carla Garbarino, Davide Orsini
    e2023019
    15-12-2023
    416
    PDF (Italian): 161
  • PO-38 | Impact of atogepant on achieving best possible quality of life among patient global impression of change responders Cristina Tassorelli,1 Pranav Gandhi,2 Molly Duan,2 Karen Carr,2 Kandavadivu Umashankar,2 Jonathan Stokes,2 Grace Forde,3 Tanya Bilchik,4 Martina Martini*, Rashmi Halker Singh5 | 1University of Pavia, Pavia, Italy; 2AbbVie, North Chicago, IL, USA; 3North American Partners in Pain Management, North New Hyde Park, NY, USA; 4Department of Neurology, Yale School of Medicine, New Haven, CT, USA; 5Mayo Clinic, Phoenix, AZ, USA *Abbvie Srl, Rome, Italy.

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15860
    257
  • PO-85 | Alterations in gut microbiota and the endocannabinoid system in an animal model of chronic migraine Sara Facchetti,1,2 Chiara Demartini,1 Miriam Francavilla,1,2 Rosaria Greco,1 Cristina Tassorelli1,2 | 1Section of Translational Neurovascular Research, IRCCS Mondino Foundation, Pavia, Italy; 2Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15909
    416
  • PO-09 | When migraine turns severe: a case of aura that lasts too long Alessandra Fera,1 Erica Agosto,1 Giulia Grasso,2 Cristina Vassia,2 Francesca Feyles,2 Carlotta Canavese,3 Sara Racalbuto,2 Antonia Versace2 | 1Department of Public Health and Pediatrics, University of Turin; 2Department of Pediatric Emergency, Pediatric Headache Centre, Regina Margherita Children’s Hospital, Turin; 3Department of Child Pathology and Care “Regina Margherita”, SSD Pediatric Neurology, Regina Margherita Children’s Hospital, Turin, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15830
    409
  • PO-52 | Long-term efficacy of CGRP mAbs: new insights and current evidence Oreste Marsico,1 Marta Lioi,2 Rosario Iannacchero,3 Michele Trimboli3 | 1Department of Neuroscience, “Giovanni Paolo II” Hospital, Lamezia Terme, Catanzaro, Italy; 2Department of Neurology, Magna Graecia University, Catanzaro, Italy; 3Institute of Neurology, AOU Renato Dulbecco, Catanzaro, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15875
    165
  • PO-23 | Hemicrania continua-like headache in familial SDHD-related paragangliomas: a diagnostic challenge A. Di Chirico, L. Curto, G. Procopio, L. Troilo, G. Siciliano, F. Baldacci, S. Gori | Neurology Unit, Department of Clinical and Experimental Medicine, University of Pisa-AOUP, Pisa, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15845
    256
  • PO-49 | Distress perception and mutuality in caregivers of migraine patients with depressive symptoms.: baseline evaluation of the observational prospective real-life MiDEAR study to evaluate the effectiveness of fremanezumab for reducing the caregivers’ burden a C. Altamura,1 L. Fofi,1 R. Ornello,2 G. Ceccardi,3 C. Aurilia,4 A. Montisano,5 I. Orologio,6 D. Mascarella,7 G. Viticchi,8 M. Marcosano,1 N. Brunelli,1 G. Del Mastro,1 A. Onofri,2 A. Lanfranchi,3 G. Fiorentini,4 M. Silvestro,6 V. Favoni,7 G. Egeo,4 M. Silvestrini,8 M. Peresson,9 S. Cevoli,7 A. Russo,6 R. Rao,3 L. Grazzi,5 S. Sacco,2 F. Vernieri1 | 1Fondazione Policlinico Universitario Campus Bio-Medico, Rome; 2University of L'Aquila, L’Aquila; 3ASST Spedali Civili di Brescia, Brescia; 4IRCCS San Raffaele, Rome; 5IRCCS Fondazione istituto Neurologico Carlo Besta, Milan; 7IRCCS Istituto Delle Scienze Neurologiche di Bologna, Bologna; 6University of Campania; Caserta; 8Marche Polytechnic University, Ancona; 9San Pietro Fatebenefratelli Hospital, Rome, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15871
    149
  • PO-19 | Unraveling the spectrum of migraine resistant to treatments: searching for novel biological PHEnotypes and theRApeutic approaches (SPHERA project) M. Giraudo,1,2 R. De Icco,1,2 G. Vaghi,1,2 V. Grillo,1,2 F. Bighiani,1,2 M. Corrado,2 A. Antoniazzi,1,2 F. Cammarota,1,2 B. Agostini,1,2 A. Solfrizzi,1,2 M. Allena,2 E. Guaschino,2 N. Ghiotto,2 R. Greco,2 C. Demartini,2 A. Zanaboni,1,2 M. Francavilla,1,2 S. Facchetti,1,2 G. Sances,2 C. Tassorelli1,2 | 1Department of Brain and Behavioral Sciences, University of Pavia; 2Headache Science and Neurorehabilitation Unit, IRCCS Mondino Foundation, Pavia, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15840
    331
  • Unbiased research is needed for rational translation of essential oils in clinic

    Damiana Scuteri, Laura Rombolà, Luigi Antonio Morrone, Shinobu Sakurada, Tsukasa Sakurada, Paolo Tonin, Giorgio Sandrini, Giacinto Bagetta, Maria Tiziana Corasaniti
    e2022027
    06-12-2022
    301
    PDF: 524
  • PO-30 | A chronic migraine phenotype unveiling acromegaly: diagnostic pitfalls and the impact of timely treatment Cinzia Rita Tamborino, Gianni Difonzo, Adriana Fallacara, Damiano Paolicelli, Maria Pia Prudenzano | Headache Center, “L. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15852
    358
  • Anti-CGRP monoclonal antibodies improve cognitive function in patients affected by chronic migraine complicated with medication overuse-headache

    Simona Guerzoni, Flavia Lo Castro, Carlo Baraldi, Daria Brovia, Fabio Tascedda, Veronica Rivi, Luca Pani
    07-05-2024
    https://doi.org/10.4081/cc.2024.15760
    3726
    PDF: 826
  • PO-82 | Integrated approach with detoxification, CGRP monoclonal antibodies and psychoeducational support in two patients with complex medication overuse headache Claudia Lanni,1 Federica Papini,2 Chiara Prevost,3 Alessandro Canessa,3 Lucia Testa,3 Cristoforo Comi,2 Delfina Ferrandi3 | 1Department of Psychology “Santi Antonio e Biagio”, University Hospital, Alessandria, Italy; 2Neurology Unit, Department of Transitional Medicine, University of Piemonte Orientale, and University Hospital “Maggiore della Carità”, Novara, Italy; 3Neurology Unit, “Santi Antonio e Biagio” University Hospital, Alessandria, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15906
    270
  • PO-46 | Diagnostic tests and headache misdiagnoses in individuals with resistant and refractory migraine – data from the REFINE study Federico De Santis,1 Chiara Rosignoli,1 Agnese Onofri,1 Mark Braschinsky,2 Olga Sved,2 Raquel Gil-Gouveia,3,4 Renato Oliveira,3 Christian Lampl,5 Jakob Paungarttner,5 Paolo Martelletti,6 William David Wells-Gatnik,7 Isabel Pavao Martins,8 Dimos D Mitsikostas,9 Loukia Apostolakopoulou,9 Aynur Ozge,10 Dilan Bayar Narin,10 Patricia Pozo-Rosich,11 Albert Munoz-Vendrell,11 Maria Pia Prudenzano,12 Martino Gentile,12 Kristina Ryliskiene,13 Jurgita Vainauskiene,14 Margarita Sanchez-del-Rio,15 Fabrizio Vernieri,16 Gianmarco Iaccarino,16 Marta Waliszewska-Prosół,17 Sławomir Budrewicz,17 Marta Carnovali,18 Zaza Katsarava,18 Simona Sacco,1 Raffaele Ornello1 | 1Department of Biotechnological and Applied Clinical Sciences, University of L’Aquila, L’Aquila, Italy; 2Department of Neurology and Neurosurgery, Institute of Clinical Medicine, Faculty of Medicine, University of Tartu and Neurology Clinic of Tartu University Hospital, Tartu, Estonia; 3Headache Center, Neurology Department, Hospital da Luz, Lisboa, Portugal; 4Center for Interdisciplinary Research in Health, Universidade Católica Portuguesa, Lisboa; 5Headache Medical Center, Seilerstaette Linz, Linz, Austria; 6Unitelma Sapienza University of Rome, Italy; 7Texas Tech University Health Sciences Center, El Paso TX, USA; 8Centro de Estudos Egas Moniz, Faculty of Medicine, University of Lisbon, Lisbon, Portugal; 9First Department of Neurology, Aeginition Hospital, National and Kapodistrian University of Athens, Athens, Greece; 10Department of Neurology, Mersin University Medical Faculty, Mersin, Turkey and NOROM Neuroscience and Neurotechnology Center of Excellence, Ankara, Turkey; 11Headache Unit, Neurology Department, Vall d’Hebron University Hospital, Headache and Neurological Pain Research Group, VHIR, Barcelona, Spain; 12Headache Center, “I. Amaducci” Neurological Clinic, Policlinico General Hospital, Bari, Italy; 13Center of Neurology, Vilnius University, Vilnius, Lithuania; 14Center of Neurology, Kardiolitos klinikos, Vilnius, Lithuania; 15Department of Neurology, Clínica Universidad de Navarra, Madrid, Spain; 16Unit of Headache and Neurosonology, Fondazione Policlinico Campus Bio-Medico and Neurology, Università Campus Bio-Medico di Roma, Roma, Italy; 17Department of Neurology, Wroclaw Medical University, Wrocław, Poland; 18Department of Neurology, Christian Hospital Unna and University of Duisburg-Essen, Ruhr Metropolitan, Germany

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15868
    239
  • Effects of botulinum toxin type A in a migraine-specific animal model

    Chiara Demartini, Rosaria Greco, Sara Facchetti, Miriam Francavilla, Anna Maria Zanaboni, Daniele Martinelli, Cristina Tassorelli
    21-05-2025
    https://doi.org/10.4081/cc.2025.15779
    1379
    PDF: 314
  • Cervello, Emicrania e altri Malditesta

    Giuseppe Nappi
    43-44
    06-05-2019
    211
    PDF: 80
  • PO-29 | Spontaneous intracranial hypotension: a clinical and radiological observational study F. Verna, D. Mascarella, V. Favoni, G. Pierangeli, L. Cirillo, S. Cevoli | IRCCS Istituto delle Scienze Neurologiche di Bologna, Italia DIBINEM, Alma Mater Studiorum Bologna, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15851
    259
  • PO-03 | Intracranial incidental findings on brain magnetic resonance imaging (MRI) in a pediatric population with primary headache: our experience and management Fabiana Ursitti,1 Filippo Tripodi,1 Laura Papetti,1 Giorgia Sforza,1 Gabriele Monte,1 Alessandro Borrelli,1 Samuela Tarantino,1 Martina Proietti Checchi,1 Massimiliano Valeriani1-3 | 1Developmental Neurology, Ospedale Pediatrico Bambino Gesù, IRCCS, Rome, Italy; 2Child Neurology Unit, Systems Medicine Department, Tor Vergata University Hospital of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Department of Health Science and Technology, School of Medicine, Aalborg University, Aalborg, Denmark

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15824
    324
  • PO-43 | Eptinezumab in migraine patients unresponsive to prior subcutaneous CGRP(-R) monoclonal antibody treatment: a retrospective case series Elena Cresta, Irene Mattioli, Michele Di Pasquale, Alice Lanfranchi, Renata Rao, Alessandro Padovani | Neurology Unit and Headache Centre, Dipartimento di continuità di cura e fragilità, ASST Spedali Civili e Università degli studi di Brescia, Brescia, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15865
    296
  • Intraparenchymal cerebral hemorrhage in a patient undergoing treatment with galcanezumab: the importance of adequate blood pressure control

    Yan Tereshko, Antonio Taglialatela, Iacopo Cancelli, Enrico Belgrado, Lorenzo Verriello, Giovanni Merlino, Mariarosaria Valente
    05-09-2025
    https://doi.org/10.4081/cc.2025.15786
    699
    PDF: 205
  • PO-89 | Alcohol and headache: an update Alessandro Panconesi,1,2 Maria Letizia Bartolozzi1 | 1Headache Centre, Department of Neurology, Health Authority, Empoli; 2Clinical Research Institute Ecomedica, Empoli, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15913
    512
  • OC-11 | Corneal nerve plexus impairment in patients with trigeminal neuralgia Daniel Litewczuk,1 Gianfranco De Stefano,1 Sabrina Compagno,2 Mattia D’Andrea,2 Ludovico Alisi,2 Marco Marenco,2 Giulia Di Stefano,1 Andrea Truini1 | 1Department of Human Neuroscience, Sapienza University of Rome, 2Department of Sense Organs, Sapienza University of Rome, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15808
    325
  • Normative values of the nociceptive blink reflex habituation

    Michele Corrado, Elena Mazzotta, Gloria Vaghi, Francescantonio Cammarota, Federico Bighiani, Alessandro Antoniazzi, Daniele Martinelli, Maria Magdalena Pocora, Luca Martinis, Valentina Grillo, Sara Bottiroli, Armando Perrotta, Giuseppe Cosentino, Grazia Sances, Cristina Tassorelli, Roberto De Icco
    07-05-2024
    https://doi.org/10.4081/cc.2024.15730
    2731
    PDF: 477
    SUPPLEMENTARY MATERIAL: 227
  • PO-02 | Migraine in youth: a double challenge to cognition and emotion Samuela Tarantino,1 Martina Proietti Checchi,1 Laura Papetti,1 Fabiana Ursitti,1 Gabriele Monte,1 Giorgia Sforza,1 Massimiliano Valeriani,1-3 | 1Developmental Neurology Unit, Bambino Gesù Children's Hospital, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Rome, Italy; 2Systems Medicine Department, Tor Vergata University of Rome, Rome, Italy; 3Translational Pain Neuroscience and Precision Medicine, CNAP, Dept. of Health Science and Technology, School of Medicine, Aalborg University, Denmark

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15823
    277
  • PO-42 | OnaBotulinumtoxin-A in chronic migraine patients with short or long disease history and psychiatric comorbidities: preliminary data from an Italian multicentric study (the BACH Study) Fabrizio Vernieri,1,2 Marilena Marcosano,2 Licia Grazzi,3 Danilo Antonio Montisano,3 Raffaele Ornello,4 Simona Sacco,4 Chiara Rosignoli,4 Alberto Doretti,5 Maria Albanese,6 Giovanna Viticchi,7 Nicoletta Brunelli, Luigi d’Onofrio,2 Luisa Fofi,1 Claudia Altamura,1,2 Patrizio Pasqualetti8 | 1Fondazione Policlinico Campus Bio-Medico, Roma, Italy; 2Università Campus Bio-Medico di Roma, Italy; 3Istituto Neurologico Besta, Milano, Italy; 4Università degli Studi l’Aquila, Italy; 5Istituto Auxologico, Milano, Italy; 6Policlinico Tor Vergata, Roma, Italy; 7Università Politecnica Marche, Italy; 8Sapienza Università di Roma, Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15864
    239
  • PO-88 | Can tamoxifen and metformin nullify efficacy of CGRP-mAbs migraine prophylaxis? Patrizia Rossi,1,2 Valentina Cima,2 Alessandro Burlina2 | 1Headache Center, 2Neurology Department, San Bassiano Hospital, Bassano del Grappa (VI), Italy

    Società Italiana per lo Studio delle Cefalee (SISC)
    06-11-2025
    https://doi.org/10.4081/cc.2025.15912
    558
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Confinia Cephalalgica

is an Open Access, peer-reviewed journal published by PAGEPress®, Pavia, Italy. All credits and honors to PKP for their OJS. eISSN 3035-0670 (Website continuously updated).

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